We found previously that long-chain fatty acids could inhibit eukaryotic DNA polymerase
activities in vitro [1, 2]. The purpose of the present study was to investigate the mode of this …

Terpenoids, 1, 2 and 3, which selectively inhibit eukaryotic DNA polymerase activities, were
isolated from the fruiting body of a basidiomycete, Ganoderma lucidum, and their structures …

Plants contain major glycoglycerolipids, such as monogalactosyl diacylglycerol (MGDG),
digalactosyl diacylglycerol (DGDG) and sulfoquinovosyl diacylglycerol (SQDG), in the …

We found and isolated two natural products in the extract from a basidiomycete, Ganoderma
lucidum, as eukaryotic DNA polymerase inhibitors. The compounds were identified as …

In screening of selective inhibitors of eukaryotic DNA polymerases (pols) for 15 years, more
than 100 inhibitors have been discovered from natural and chemical sources. Some …

As described previously, we found that new triterpenoid compounds, designated fomitellic
acids A and B, which selectively inhibit the activities of mammalian DNA polymerases α and …

Three sulfolipid compounds, 1, 2 and 3, have been isolated from a higher plant, a
pteridophyte, Athyrium niponicum, as potent inhibitors of the activities of calf DNA …

Sulfoquinovosyldiacylglycerols (SQDGs) and sulfoquinovosylmonoacylglycerols (SQMGs),
bearing diverse fatty acids, were synthesized from d-glucose, and were examined for …

Four new triterpenoid compounds, 1− 4, were isolated from the mycelium of a
basidiomycete, Fomitella fraxinea, and their structures determined by spectroscopic …

We chemically synthesized epolactaene, a neuritogenic compound in human
neuroblastoma cells, and investigated its biochemical action in vitro. Epolactaene and its …