High-dose intravenous vitamin C, a promising multi-targeting agent in the treatment of cancer

F Böttger, A Vallés-Martí, L Cahn… - Journal of experimental & …, 2021 - Springer
Mounting evidence indicates that vitamin C has the potential to be a potent anti-cancer
agent when administered intravenously and in high doses (high-dose IVC). Early phase …

Insight on nano drug delivery systems with targeted therapy in treatment of oral cancer

K Vyas, M Rathod, MM Patel - Nanomedicine: Nanotechnology, Biology …, 2023 - Elsevier
Oral cancer is a type of cancer that develops in the mouth and is one of the deadliest
malignancies in the world. Currently surgical, radiation therapy, and chemotherapy are most …

Nanoparticles in dentistry: A comprehensive review

G Moraes, C Zambom, WL Siqueira - Pharmaceuticals, 2021 - mdpi.com
In recent years, nanoparticles (NPs) have been receiving more attention in dentistry. Their
advantageous physicochemical and biological properties can improve the diagnosis …

Polyelectrolyte three layer nanoparticles of chitosan/dextran sulfate/chitosan for dual drug delivery

F Wang, J Li, X Tang, K Huang, L Chen - Colloids and Surfaces B …, 2020 - Elsevier
In this work, dual drug loaded in chitosan/dextran sulfate/chitosan (CS/DEX/CS)
nanoparticles was synthesized by layer-by-layer (LBL) self-assembly technique for use in …

Ganoderma lucidum polysaccharides inhibit in vitro tumorigenesis, cancer stem cell properties and epithelial-mesenchymal transition in oral squamous cell carcinoma

MR de Camargo, TF Frazon, KK Inacio… - Journal of …, 2022 - Elsevier
Ethnopharmacological relevance The polysaccharides of the millenary mushroom
Ganoderma lucidum (GL) have been shown for decades to present anti-tumor activities, but …

Nanoparticle-mediated active and passive drug targeting in oral squamous cell carcinoma: current trends and advances

J Manikkath, A Manikkath, H Lad, LK Vora… - …, 2023 - Taylor & Francis
Oral squamous cell carcinoma (OSCC) is an invasive and highly malignant cancer with
significant morbidity and mortality. Existing treatments including surgery, chemotherapy and …

Combination therapy as a promising way to fight oral cancer

JPN Silva, B Pinto, L Monteiro, PMA Silva, H Bousbaa - Pharmaceutics, 2023 - mdpi.com
Oral cancer is a highly aggressive tumor with invasive properties that can lead to metastasis
and high mortality rates. Conventional treatment strategies, such as surgery, chemotherapy …

Nano-drug delivery systems in oral cancer therapy: recent developments and prospective

Y Zhang, Y Wu, H Du, Z Li, X Bai, Y Wu, H Li, M Zhou… - Pharmaceutics, 2023 - mdpi.com
Oral cancer (OC), characterized by malignant tumors in the mouth, is one of the most
prevalent malignancies worldwide. Chemotherapy is a commonly used treatment for OC; …

Ascorbate as a bioactive compound in cancer therapy: the old classic strikes Back

J González-Montero, S Chichiarelli, M Eufemi, F Altieri… - Molecules, 2022 - mdpi.com
Cancer is a disease of high mortality, and its prevalence has increased steadily in the last
few years. However, during the last decade, the development of modern chemotherapy …

Nanoparticles as drug delivery systems in the treatment of oral squamous cell carcinoma: current status and recent progression

S Cui, H Liu, G Cui - Frontiers in Pharmacology, 2023 - frontiersin.org
Oral squamous cell carcinoma (OSCC) is a common human malignancy with an estimated
incidence of around 377,713 new cases worldwide in 2020. Despite the advance in clinical …