Transition metal complexes are of increasing interest as photosensitizers in photodynamic
therapy (PDT) and, more recently, for photochemotherapy (PCT). In recent years, Ru (II) …

Cisplatin is one of the most widely used chemotherapeutic agents for various solid tumors in
the clinic due to its high efficacy and broad spectrum. The antineoplastic activity of cisplatin …

The immune system deploys a multitude of innate and adaptive mechanisms not only to
ward off pathogens but also to prevent malignant transformation (“immune surveillance”) …

The synergistic action of light, oxygen and a photosensitizer (PS) has found applications for
decades in medicine under the name of photodynamic therapy (PDT) for the treatment of …

In this review we summarize our work on development of Ru complexes with potential
antitumor activity, which was performed over the last few years. In order to establish the …

Countless expectations converge in the multidisciplinary endeavour for the search and
development of effective and safe drugs in fighting cancer. Although they still embody a …

Studies of metal uptake, metabolism and excretion by single bacterial, yeast, plant and
animal cells is a widespread area of research, yet little is known about the reactivity and …

Ruthenium (II)-based coordination complexes have emerged as photosensitizers (PSs) for
photodynamic therapy (PDT) in oncology as well as antimicrobial indications and have great …

Breast cancer is one of the most frequently diagnosed cancers that is threatening women's
life. Current clinical treatment regimens for breast cancer often involve neoadjuvant and …

8-Hydroxyquinoline and its derivatives have a broad variety of pharmacological properties,
which make them an ideal bioactive building block in the development of metal-based …