Background: Histone deacetylases (HDAC) are an important class of enzymes that play a
pivotal role in epigenetic regulation of gene expression that modifies the terminal of core …

Cancer is one of the primary causes of mortality worldwide. Despite nowadays are
numerous therapeutic treatments to fight tumor progression, it is still challenging to …

4-Carboxy-α-[3-(hydroxyamino)-3-oxopropyl]-benzenepropanoic acid 1 is a potent
hydroxamate-based inhibitor of glutamate carboxypeptidase II. In an attempt to improve its …

Histone deacetylase inhibitors are the most important class of drugs for the treatment of
oncology and other diseases due to their effect on cell growth, differentiation, and apoptosis …

Ингибиторы гистондеацетилаз-важнейший класс лекарственных средств для лечения
онкологических и других заболеваний из-за их влияния на рост, дифференцировку и …

NAD (P)+-зависимая формиатдегидрогеназа (КФ 1.2. 1.2, FDH) катализирует простую с
точки зрения химии и биологии реакцию окисления формиат-иона до углекислого газа …