Clearance pathways and tumor targeting of imaging nanoparticles

M Yu, J Zheng - ACS nano, 2015 - ACS Publications
A basic understanding of how imaging nanoparticles are removed from the normal
organs/tissues but retained in the tumors is important for their future clinical applications in …

[HTML][HTML] Renal clearable inorganic nanoparticles: a new frontier of bionanotechnology

J Liu, M Yu, C Zhou, J Zheng - Materials Today, 2013 - Elsevier
While inorganic nanoparticles (NPs) with tunable and diverse material properties open up
unprecedented opportunities for novel biomedical technologies, translating these NPs into …

Passive tumor targeting of renal-clearable luminescent gold nanoparticles: long tumor retention and fast normal tissue clearance

J Liu, M Yu, C Zhou, S Yang, X Ning… - Journal of the American …, 2013 - ACS Publications
Glutathione-coated luminescent gold nanoparticles (GS-AuNPs) with diameters of∼ 2.5 nm
behave like small dye molecules (IRDye 800CW) in physiological stability and renal …

Chitosan-based nanoparticle co-delivery of docetaxel and curcumin ameliorates anti-tumor chemoimmunotherapy in lung cancer

X Zhu, Z Yu, L Feng, L Deng, Z Fang, Z Liu, Y Li… - Carbohydrate …, 2021 - Elsevier
The application of traditional chemotherapy drugs for lung cancer has obvious limitations,
such as toxic side effects, uncontrolled drug-release, poor bioavailability, and drug …

Positron emission tomography (PET) imaging with 18F-based radiotracers

MM Alauddin - American journal of nuclear medicine and …, 2011 - pmc.ncbi.nlm.nih.gov
Positron Emission Tomography (PET) is a nuclear medicine imaging technique that is widely
used in early detection and treatment follow up of many diseases, including cancer. This …

[PDF][PDF] Near‐infrared emitting radioactive gold nanoparticles with molecular pharmacokinetics

C Zhou, G Hao, P Thomas, J Liu, M Yu… - Angewandte Chemie …, 2012 - academia.edu
Contrast agents used in clinics often exhibit the following pharmacokinetics: rapid diffusion
(short distribution half-life t1/2α), relatively long blood circulation time (long elimination half …

Ultrasmall luminescent metal nanoparticles: surface engineering strategies for biological targeting and imaging

X Luo, J Liu - Advanced Science, 2022 - Wiley Online Library
In the past decade, ultrasmall luminescent metal nanoparticles (ULMNPs, d< 3 nm) have
achieved rapid progress in addressing many challenges in the healthcare field because of …

Systematically evaluating DOTATATE and FDG as PET immuno-imaging tracers of cardiovascular inflammation

YC Toner, AA Ghotbi, S Naidu, K Sakurai… - Scientific reports, 2022 - nature.com
In recent years, cardiovascular immuno-imaging by positron emission tomography (PET)
has undergone tremendous progress in preclinical settings. Clinically, two approved PET …

Safety evaluation of nanotechnology products

AJ Domb, G Sharifzadeh, V Nahum, H Hosseinkhani - Pharmaceutics, 2021 - mdpi.com
Nanomaterials are now being used in a wide variety of biomedical applications. Medical and
health-related issues, however, have raised major concerns, in view of the potential risks of …

Precisely regulated luminescent gold nanoparticles for identification of cancer metastases

Y Tan, K He, B Tang, H Chen, Z Zhao, C Zhang, L Lin… - ACS …, 2020 - ACS Publications
The nanoprobes for identification of cancer metastases in the mononuclear phagocyte
system (MPS) organs are of significant importance but are limited due to the long-standing …