Pharmacogenetics in primary headache disorders

II Belyaeva, AG Subbotina, II Eremenko… - Frontiers in …, 2022 - frontiersin.org
Primary headache disorders, such as migraine, tension-type headache (TTH), and cluster
headache, belong to the most common neurological disorders affecting a high percentage of …

Anthocyanin composition of fruit extracts from Lycium ruthenicum and their protective effect for gouty arthritis

G Zhang, S Chen, WU Zhou, J Meng, K Deng… - Industrial Crops and …, 2019 - Elsevier
Lycium ruthenicum Murray (LR) represents an agricultural cash crop found in Northwest
China and has been used in traditional folk medicine for a long time. However, detailed …

Potential of natural bioactive C-glycosyl flavones for antidiabetic properties

LS Chua, FI Abdullah, MA Awang - Studies in Natural Products Chemistry, 2020 - Elsevier
Diabetes mellitus is a major health problem in all parts of the world. It is a serious endocrine
syndrome and affects the metabolism of carbohydrates, fats, and proteins in the human …

Structural modification of aspirin to design a new potential cyclooxygenase (COX-2) inhibitors

M Uzzaman, T Mahmud - In Silico Pharmacology, 2020 - Springer
Aspirin (Asp) is one of the most important and ancient member of nonsteroidal anti-
inflammatory drugs (NSAID), commonly used in medication of fever, pain and inflammation …

Microwave-Assisted Synthesis, In Vivo Anti-Inflammatory and In Vitro Anti-Oxidant Activities, and Molecular Docking Study of New Substituted Schiff Base Derivatives

M Hanif, M Hassan, M Rafiq, Q Abbas, A Ishaq… - Pharmaceutical …, 2018 - Springer
In view of considerable interest in the design and synthesis of new heterocyclic compounds
with promising biological activities for medical and biological applications, a series of eight …

Tumor-promoting function of single nucleotide polymorphism rs1836724 (C3388T) alters multiple potential legitimate microRNA binding sites at the 3'-untranslated …

F Bagheri, H Mesrian Tanha… - Molecular …, 2016 - spandidos-publications.com
ErbB4 can act as either a tumor-suppressor gene or an oncogene in breast cancer. Multiple
genetic factors including single nucleotide polymorphisms (SNPs) affect gene expression …

Flurbiprofen–antioxidant mutual prodrugs as safer nonsteroidal anti-inflammatory drugs: synthesis, pharmacological investigation, and computational molecular …

Z Ashraf, Alamgeer, M Kanwal, M Hassan… - Drug design …, 2016 - Taylor & Francis
Flurbiprofen–antioxidant mutual prodrugs were synthesized to reduce the gastrointestinal
(GI) effects associated with flurbiprofen. For reducing the GI toxicity, the free carboxylic group …

Lipophilic index of serum phospholipids in patients with type 2 diabetes and atherosclerotic cardiovascular disease: links with metabolic control, vascular inflammation …

P Rostoff, D Drwiła-Stec, A Majda, K Stępień… - Cardiovascular …, 2024 - Springer
Background Little is known about the mechanisms underlying the association of the serum
phospholipid lipophilic index (LI) with atherosclerotic cardiovascular disease (ASCVD) in …

Extrapolation of hydroxytyrosol and its analogues as potential anti-inflammatory agents

N Kumar, B Gorai, S Gupta, Shiva… - Journal of Biomolecular …, 2021 - Taylor & Francis
Discovery of potential lead molecule is a challenging, and complex process which require
lots of money, patience, and manpower. Human beings are using natural products …

[PDF][PDF] Effects of solvent polarity on solvation free energy, dipole moment, polarizability, hyperpolarizability and molecular reactivity of aspirin

MF Khan, RB Rashid, MM Rahman… - Int. J. Pharm. Pharm …, 2017 - academia.edu
Objective: The aim of the study is to explore the effects of solvent polarity on solvation free
energy, dipole moment, polarizability, first order hyperpolarizability and different molecular …