The effects of drugs on membrane fluidity.

DB Goldstein - Annual Review of Pharmacology and Toxicology, 1984 - europepmc.org
Anesthetics almost always disorder or" fluidize" membranes, ie the drugs increase the
mobility of spin labels and reduce order parameters. This effect is universal at high …

Cellular effects of cannabinoids.

BR Martin - Pharmacological reviews, 1986 - pharmrev.aspetjournals.org
The many studies that have been included in this review suggest that cannabinoids have
ubiquitous effects on biological systems. These results also underscore the intensity to …

[27] Measurement of substrate and inhibitor binding to microsomal cytochrome P-450 by optical-difference spectroscopy

CR Jefcoate - Methods in enzymology, 1978 - Elsevier
Publisher Summary This chapter discusses the measurement of substrate and inhibitor
binding to microsomal cytochrorne P-450 by optical-difference spectroscopy. Difference …

[图书][B] Guide to cytochromes P450: structure and function

DFV Lewis - 1996 - taylorfrancis.com
This book covers the relevant aspects of cytochromes P450 for understanding their structure,
function and mechanisms of action, such as physicochemical characterization methods …

[图书][B] Cytochromes

DFV Lewis - 2003 - books.google.com
Page 1 Cytochromes P450 Structure, Function and Mechanism David FV Lewis Also
available as a printed book see title verso for ISBN details Page 2 Cytochromes P450 …

Effects of flavonoids on aromatase activity, an in vitro study

C Pelissero, MJP Lenczowski, D Chinzi… - The Journal of steroid …, 1996 - Elsevier
In the study, the inhibitory effect of flavonoids, including isoflavonic phytoestrogens, on the
ovarian aromatase enzyme complex from the rainbow trout, Oncorhynchus mykiss, was …

Reevaluating equilibrium and kinetic binding parameters for lipophilic drugs based on a structural model for drug interactions with biological membranes

RP Mason, DG Rhodes… - Journal of medicinal …, 1991 - ACS Publications
Introduction Structure-function activity relationships of drugs that bind to certain membrane-
associated receptors must take into account the local membrane bilayer environment where …

[图书][B] Cytochrome P-450 and active oxygen

AI Archakov, GI Bachmanova - 1990 - elibrary.ru
Cytochrome P-450 and Active Oxygen КОРЗИНА ПОИСК НАВИГАТОР ЖУРНАЛЫ КНИГИ
ПАТЕНТЫ ПОИСК АВТОРЫ ОРГАНИЗАЦИИ КЛЮЧЕВЫЕ СЛОВА РУБРИКАТОР …

Outside-inside translocation of aminophospholipids in the human erythrocyte membrane is mediated by a specific enzyme

A Zachowski, E Favre, S Cribier, P Herve… - Biochemistry, 1986 - ACS Publications
Revised Manuscript Received December 20, 1985 abstract: When human erythrocytes are
incubated with spin-labeled analogues of sphingomyelin, phosphatidylcholine …

Lipid bilayer properties control membrane partitioning, binding, and transport of p-glycoprotein substrates

AT Clay, FJ Sharom - Biochemistry, 2013 - ACS Publications
The ABC protein P-glycoprotein (Pgp or ABCB1) is a multidrug efflux pump capable of
transporting many structurally diverse substrates from within the lipid bilayer. Previous …