A review of the biological role of miRNAs in prostate cancer suppression and progression

AS Doghish, A Ismail, HA El-Mahdy, MA Elkady… - International journal of …, 2022 - Elsevier
Prostate cancer (PC) is the third-leading cause of cancer-related deaths worldwide.
Although the current treatment strategies are progressing rapidly, PC is still representing a …

Influence of miRNA in insulin signaling pathway and insulin resistance: micro‐molecules with a major role in type‐2 diabetes

C Chakraborty, CGP Doss… - Wiley …, 2014 - Wiley Online Library
The prevalence of type‐2 diabetes (T2D) is increasing significantly throughout the globe
since the last decade. This heterogeneous and multifactorial disease, also known as insulin …

[HTML][HTML] MicroRNAs: processing, maturation, target recognition and regulatory functions

GC Shukla, J Singh, S Barik - Molecular and cellular pharmacology, 2011 - ncbi.nlm.nih.gov
The remarkable discovery of small noncoding microRNAs (miRNAs) and their role in
posttranscriptional gene regulation have revealed another fine-tuning step in the expression …

The endothelial-specific microRNA miR-126 governs vascular integrity and angiogenesis

S Wang, AB Aurora, BA Johnson, X Qi, J McAnally… - Developmental cell, 2008 - cell.com
Endothelial cells play essential roles in maintenance of vascular integrity, angiogenesis, and
wound repair. We show that an endothelial cell-restricted microRNA (miR-126) mediates …

AngiomiRs—key regulators of angiogenesis

S Wang, EN Olson - Current opinion in genetics & development, 2009 - Elsevier
The formation of new blood vessels through the process of angiogenesis is critical in
vascular development and homeostasis. Aberrant angiogenesis leads to a variety of …

miR-34a inhibits migration and invasion by down-regulation of c-Met expression in human hepatocellular carcinoma cells

N Li, H Fu, Y Tie, Z Hu, W Kong, Y Wu, X Zheng - Cancer letters, 2009 - Elsevier
Several studies have shown that miR-34a represses the expression of many genes and
induces G1 arrest, apoptosis, and senescence. In the present study, we identified the role of …

Identification of restricted subsets of mature microRNA abnormally expressed in inactive colonic mucosa of patients with inflammatory bowel disease

M Fasseu, X Tréton, C Guichard, E Pedruzzi… - PloS one, 2010 - journals.plos.org
Background Ulcerative Colitis (UC) and Crohn's Disease (CD) are two chronic Inflammatory
Bowel Diseases (IBD) affecting the intestinal mucosa. Current understanding of IBD …

Deep sequencing of RNA from three different extracellular vesicle (EV) subtypes released from the human LIM1863 colon cancer cell line uncovers distinct miRNA …

H Ji, M Chen, DW Greening, W He, A Rai, W Zhang… - PloS one, 2014 - journals.plos.org
Secreted microRNAs (miRNAs) enclosed within extracellular vesicles (EVs) play a pivotal
role in intercellular communication by regulating recipient cell gene expression and affecting …

The role of miR-126 in embryonic angiogenesis, adult vascular homeostasis, and vascular repair and its alterations in atherosclerotic disease

DA Chistiakov, AN Orekhov, YV Bobryshev - Journal of molecular and …, 2016 - Elsevier
Abstract Expression of microRNA (miR)-126 is enriched in endothelial cells (ECs) and
endothelial progenitor cells (EPCs). MiR-126 is considered a master regulator of …

The role of microRNAs in endometriosis and associated reproductive conditions

EMC Ohlsson Teague, CG Print… - Human reproduction …, 2010 - academic.oup.com
BACKGROUND microRNAs (miRNAs) are short, single-stranded RNAs that regulate gene
expression at the post-transcriptional level. Recent research has shown that miRNAs and …