[HTML][HTML] Mutations in SARS-CoV-2: Insights on structure, variants, vaccines, and biomedical interventions

AI Abulsoud, HM El-Husseiny, AA El-Husseiny… - Biomedicine & …, 2023 - Elsevier
COVID-19 is a worldwide pandemic caused by SARS-coronavirus-2 (SARS-CoV-2). Less
than a year after the emergence of the Covid-19 pandemic, many vaccines have arrived on …

Beneath the skin: a review of current trends and future prospects of transdermal drug delivery systems

AZ Alkilani, J Nasereddin, R Hamed, S Nimrawi… - Pharmaceutics, 2022 - mdpi.com
The ideal drug delivery system has a bioavailability comparable to parenteral dosage forms
but is as convenient and easy to use for the patient as oral solid dosage forms. In recent …

Adjuvant physiochemistry and advanced nanotechnology for vaccine development

H Ren, W Jia, Y Xie, M Yu, Y Chen - Chemical Society Reviews, 2023 - pubs.rsc.org
Vaccines comprising innovative adjuvants are rapidly reaching advanced translational
stages, such as the authorized nanotechnology adjuvants in mRNA vaccines against COVID …

Wearable Clinic: From Microneedle‐Based Sensors to Next‐Generation Healthcare Platforms

H Sun, Y Zheng, G Shi, H Haick, M Zhang - Small, 2023 - Wiley Online Library
The rapid development of wearable biosensing calls for next‐generation devices that allow
continuous, real‐time, and painless monitoring of health status along with responsive …

Direct Presentation of Tumor‐Associated Antigens to Induce Adaptive Immunity by Personalized Dendritic Cell‐Mimicking Nanovaccines

J Zhang, B Fan, G Cao, W Huang, F Jia… - Advanced …, 2022 - Wiley Online Library
Dendritic cells (DCs)‐based vaccines are an approved method for inducing potent antigen‐
specific immune responses to eliminate tumor cells. However, this promising strategy still …

Dissolvable polymer microneedles for drug delivery and diagnostics

M Ali, S Namjoshi, HAE Benson, Y Mohammed… - Journal of Controlled …, 2022 - Elsevier
Dissolvable transdermal microneedles (μND) are promising micro-devices used to transport
a wide selection of active compounds into the skin. To provide an effective therapeutic …

Emerging wearable chemical sensors enabling advanced integrated systems toward personalized and preventive medicine

T He, F Wen, Y Yang, X Le, W Liu, C Lee - Analytical Chemistry, 2023 - ACS Publications
With the rise of silicon-based semiconductor technology in the 1950s, people's lives have
been dramatically transformed by the information technology industry. 1 For instance …

[HTML][HTML] DNA vaccines: history, molecular mechanisms and future perspectives

S Pagliari, B Dema, A Sanchez-Martinez… - Journal of Molecular …, 2023 - Elsevier
The history of DNA vaccine began as early as the 1960s with the discovery that naked DNA
can transfect mammalian cells in vivo. In 1992, the evidence that such transfection could …

Microneedle-mediated transdermal delivery of biopharmaceuticals

HX Nguyen, CN Nguyen - Pharmaceutics, 2023 - mdpi.com
Transdermal delivery provides numerous benefits over conventional routes of
administration. However, this strategy is generally limited to a few molecules with specific …

[HTML][HTML] Advances in the polymeric delivery of nucleic acid vaccines

G Chen, B Zhao, EF Ruiz, F Zhang - Theranostics, 2022 - ncbi.nlm.nih.gov
Nucleic acid vaccines, especially messenger RNA (mRNA) vaccines, display unique
benefits in the current COVID-19 pandemic. The application of polymeric materials as …