Haematological management of major haemorrhage: a British Society for Haematology guideline

SJ Stanworth, K Dowling, N Curry… - British journal of …, 2022 - Wiley Online Library
Background Major haemorrhage is a clinical emergency that results in morbidity and
mortality: practice guidance is important to reduce these risks. Delayed recognition of …

Massive hemorrhage protocol: a practical approach to the bleeding trauma patient

A Petrosoniak, K Pavenski, LT da Luz… - Emergency Medicine …, 2023 - emed.theclinics.com
A focused assessment with sonography in trauma examination is positive for free fluid in the
right upper quadrant. There is no evidence of pneumothorax on ultrasound. Her pelvis is …

Hemostatic defects in massive transfusion: an update and treatment recommendations

LM Napolitano - Expert Review of Hematology, 2021 - Taylor & Francis
Introduction Acute hemorrhage is a global healthcare issue, and remains the leading
preventable cause of death in trauma. Acute severe hemorrhage can be related to traumatic …

Guideline No. 431: postpartum hemorrhage and hemorrhagic shock

M Basso, C Chan, K Duckitt, R Lett - Journal of Obstetrics and …, 2022 - Elsevier
Objective This guideline aims to provide evidence for prevention, recognition, and treatment
of postpartum hemorrhage including severe hemorrhage leading to hemorrhagic shock …

Protocol for a multicentre, randomised, parallel-control, superiority trial comparing administration of clotting factor concentrates with a standard massive haemorrhage …

LT da Luz, J Callum, A Beckett, HP Hucke, J Carroll… - BMJ open, 2021 - bmjopen.bmj.com
Introduction Acute traumatic coagulopathy (ATC) in bleeding trauma patients increase in-
hospital mortality. Fibrinogen concentrate (FC) and prothrombin complex concentrate (PCC) …

Development of a national out-of-hospital transfusion protocol: a modified RAND Delphi study

J von Vopelius-Feldt, J Lockwood, S Mal… - … Open Access Journal, 2023 - cmajopen.ca
Background: Early resuscitation with blood components or products is emerging as best
practice in selected patients with trauma and medical patients; as a result, out-of-hospital …

Correction of haemorrhagic shock-associated coagulopathy and impaired haemostasis by plasma, prothrombin complex concentrates or an activated protein C …

LJ Eltringham-Smith, SC Meixner, ELG Pryzdial… - Scientific Reports, 2023 - nature.com
Even with extensive transfusion support, trauma-induced bleeding often leads to death.
Early intervention may improve outcomes, yet which blood products, factor concentrates, or …

Nutrient supplementation of culture media improves the detection of Cutibacterium acnes in platelet components by an automated culture system

D Kumaran, S Ramirez‐Arcos - Vox Sanguinis, 2023 - Wiley Online Library
Abstract Background and Objectives Platelet concentrates (PCs) contaminated with
Cutibacterium acnes are often transfused prior to detection by the BACT/ALERT system …

[PDF][PDF] International forum on the management of major haemorrhage: summary

L Green, S Stanworth, Z McQuilten, V Lin, H Tucker… - Vox …, 2022 - qmro.qmul.ac.uk
Acute bleeding that requires large volume transfusions can occur in any clinical setting [1–
3]. The optimal management of this type of bleeding is complex and has a major cost burden …

Anaesthesia for vascular emergencies–a state of the art review

N Boucher, H Dreksler, J Hooper, S Nagpal… - …, 2023 - Wiley Online Library
In this state‐of‐the‐art review, we discuss the presenting symptoms and management
strategies for vascular emergencies. Although vascular emergencies are best treated at a …