534 Hypertension September 2016 vasodilation is unrelated to the tissue kallikrein–kinin
system. 18 In addition, kallistatin transgenic mice were found to have significantly lower …

Kallistatin was identified in human plasma as a tissue kallikrein‐binding protein and a serine
proteinase inhibitor. Kallistatin exerts pleiotropic effects on angiogenesis, oxidative stress …

The increasing availability of multivariate data within biomedical research calls for
appropriate statistical methods that can describe and model complex relationships between …

Kallistatin is an endogenous protein that regulates differential signaling pathways and
biological functions. Our previous studies showed that kallistatin gene therapy inhibited …

Kallistatin (KS) has been recognized as a plasma protein with anti-inflammatory functions.
Macrophages are the primary inflammatory cells in atherosclerotic plaques. However, it is …

Objective Kallistatin (KST), also known as SERPIN A4, is a circulating, broadly acting human
plasma protein with pleiotropic properties. Clinical studies in humans revealed reduced KST …

Prolonged inflammation and oxidative stress are emerging as key causes of pathological
wound healing and the development of liver fibrosis. We have investigated the effects of …

Objective Kallistatin plays an important role in the inhibition of inflammation, oxidative stress,
fibrosis and angiogenesis. We aimed to determine the impact of kallistatin on obesity and its …

Kallistatin, via its two structural elements–an active site and a heparin-binding domain–
displays a double-edged function in angiogenesis, apoptosis and oxidative stress. First …

Group A streptococcus (GAS) infection may cause severe life-threatening diseases,
including necrotizing fasciitis and streptococcal toxic shock syndrome. Despite the …