[HTML][HTML] Dengue virus infection–a review of pathogenesis, vaccines, diagnosis and therapy

BH Kok, HT Lim, CP Lim, NS Lai, CY Leow, CH Leow - Virus research, 2023 - Elsevier
The transmission of dengue virus (DENV) from an infected Aedes mosquito to a human,
causes illness ranging from mild dengue fever to fatal dengue shock syndrome. The similar …

[HTML][HTML] Viral membrane fusion

SC Harrison - Virology, 2015 - Elsevier
Membrane fusion is an essential step when enveloped viruses enter cells. Lipid bilayer
fusion requires catalysis to overcome a high kinetic barrier; viral fusion proteins are the …

A single mutation in the prM protein of Zika virus contributes to fetal microcephaly

L Yuan, XY Huang, ZY Liu, F Zhang, XL Zhu, JY Yu… - Science, 2017 - science.org
Zika virus (ZIKV) has evolved into a global health threat because of its unexpected causal
link to microcephaly. Phylogenetic analysis reveals that contemporary epidemic strains have …

Zika virus structure, maturation, and receptors

D Sirohi, RJ Kuhn - The Journal of infectious diseases, 2017 - academic.oup.com
The emergence of Zika virus (ZIKV) as a major public health threat has focused research on
understanding virus biology and developing a suite of strategies for disease intervention …

LoFreq: a sequence-quality aware, ultra-sensitive variant caller for uncovering cell-population heterogeneity from high-throughput sequencing datasets

A Wilm, PPK Aw, D Bertrand, GHT Yeo… - Nucleic acids …, 2012 - academic.oup.com
The study of cell-population heterogeneity in a range of biological systems, from viruses to
bacterial isolates to tumor samples, has been transformed by recent advances in …

The structure of immature tick-borne encephalitis virus supports the collapse model of flavivirus maturation

M Anastasina, T Füzik, A Domanska, LIA Pulkkinen… - Science …, 2024 - science.org
We present structures of three immature tick-borne encephalitis virus (TBEV) isolates. Our
atomic models of the major viral components, the E and prM proteins, indicate that the pr …

New insights into the immunopathology and control of dengue virus infection

G Screaton, J Mongkolsapaya, S Yacoub… - Nature Reviews …, 2015 - nature.com
Dengue virus poses a major threat to global public health: two-thirds of the world's
population is now at risk from infection by this mosquito-borne virus. Dengue virus causes a …

A new class of highly potent, broadly neutralizing antibodies isolated from viremic patients infected with dengue virus

W Dejnirattisai, W Wongwiwat, S Supasa, X Zhang… - Nature …, 2015 - nature.com
Dengue is a rapidly emerging, mosquito-borne viral infection, with an estimated 400 million
infections occurring annually. To gain insight into dengue immunity, we characterized 145 …

Dengue virus infection: a tale of viral exploitations and host responses

N Nanaware, A Banerjee, S Mullick Bagchi, P Bagchi… - Viruses, 2021 - mdpi.com
Dengue is a mosquito-borne viral disease (arboviral) caused by the Dengue virus. It is one
of the prominent public health problems in tropical and subtropical regions with no effective …

The bright and the dark side of human antibody responses to flaviviruses: lessons for vaccine design

FA Rey, K Stiasny, MC Vaney, M Dellarole… - EMBO reports, 2018 - embopress.org
Zika and dengue viruses belong to the Flavivirus genus, a close group of antigenically
related viruses that cause significant arthropod‐transmitted diseases throughout the globe …