Drug delivery and nanoparticles: applications and hazards
WH De Jong, PJA Borm - International journal of nanomedicine, 2008 - Taylor & Francis
The use of nanotechnology in medicine and more specifically drug delivery is set to spread
rapidly. Currently many substances are under investigation for drug delivery and more …
rapidly. Currently many substances are under investigation for drug delivery and more …
Development of L-asparaginase biobetters: current research status and review of the desirable quality profiles
LP Brumano, FVS da Silva, TA Costa-Silva… - … in bioengineering and …, 2019 - frontiersin.org
L-Asparaginase (ASNase) is a vital component of the first line treatment of acute
lymphoblastic leukemia (ALL), an aggressive type of blood cancer expected to afflict over …
lymphoblastic leukemia (ALL), an aggressive type of blood cancer expected to afflict over …
Enzyme engineering: Reshaping the biocatalytic functions
Enzyme engineering is a powerful tool to fine‐tune the enzymes. It is a technique by which
the stability, activity, and specificity of the enzymes can be altered. The characteristic …
the stability, activity, and specificity of the enzymes can be altered. The characteristic …
L-asparaginase: a promising chemotherapeutic agent
This article comprises detailed information about L-asparaginase, encompassing topics
such as microbial and plant sources of L-asparaginase, treatment with L-asparaginase …
such as microbial and plant sources of L-asparaginase, treatment with L-asparaginase …
Recent Strategies and Applications for l-Asparaginase Confinement
l-asparaginase (ASNase, EC 3.5. 1.1) is an aminohydrolase enzyme with important uses in
the therapeutic/pharmaceutical and food industries. Its main applications are as an …
the therapeutic/pharmaceutical and food industries. Its main applications are as an …
Sequential BMP‐2/BMP‐7 delivery from polyester nanocapsules
P Yilgor, N Hasirci, V Hasirci - … Part A: An Official Journal of The …, 2010 - Wiley Online Library
The aim of this study was to develop a nanosized, controlled growth factor release system to
incorporate into tissue engineering scaffolds and thus activate the cells seeded in the …
incorporate into tissue engineering scaffolds and thus activate the cells seeded in the …
Cell-penetrating peptides meditated encapsulation of protein therapeutics into intact red blood cells and its application
H He, J Ye, Y Wang, Q Liu, HS Chung, YM Kwon… - Journal of Controlled …, 2014 - Elsevier
Red blood cells (RBCs) based drug carrier appears to be the most appealing for protein
drugs due to their unmatched biocompatability, biodegradability, and long lifespan in the …
drugs due to their unmatched biocompatability, biodegradability, and long lifespan in the …
Nanoparticulate carriers (NPC) for oral pharmaceutics and nutraceutics
CM Lopes, P Martins-Lopes… - Die Pharmazie-An …, 2010 - ingentaconnect.com
The introduction of nanoparticulate carriers (NPC) in the pharmaceutic and nutraceutic fields
has changed the definitions of disease management and treatment, diagnosis, as well as …
has changed the definitions of disease management and treatment, diagnosis, as well as …
L-asparaginase immobilization in supramolecular nanogels of PEG-grafted poly HPMA and bis (α-cyclodextrin) to enhance pharmacokinetics and lower enzyme …
L-asparaginase (ASNase) enzyme has limited therapeutic use due to its poor
pharmacokinetics and immunogenicity. To overcome these obstacles, we immobilized …
pharmacokinetics and immunogenicity. To overcome these obstacles, we immobilized …
Encapsulation of Ellipticine in poly-(3-hydroxybutyrate-co-3-hydroxyvalerate) based nanoparticles and its in vitro application
Biodegradable, biocompatible, renewable and non-toxic polyhydroxyalkanoates (PHAs)
based nanoparticles are the novel nanotherapeutic tool which are used for the …
based nanoparticles are the novel nanotherapeutic tool which are used for the …