Liquid biopsies: applications for cancer diagnosis and monitoring

I Martins, IP Ribeiro, J Jorge, AC Gonçalves… - Genes, 2021 - mdpi.com
The minimally—or non-invasive detection of circulating tumor-derived components in
biofluids, such as blood, liquid biopsy is a revolutionary approach with significant potential …

Biomarkers for early detection, prognosis, and therapeutics of esophageal cancers

V Rai, J Abdo, DK Agrawal - International Journal of Molecular Sciences, 2023 - mdpi.com
Esophageal cancer (EC) is the deadliest cancer worldwide, with a 92% annual mortality rate
per incidence. Esophageal squamous cell carcinoma (ESCC) and esophageal …

Analysis of circulating tumor DNA to predict risk of recurrence in patients with esophageal and gastric cancers

BM Huffman, VN Aushev, GL Budde, J Chao… - JCO Precision …, 2022 - ascopubs.org
PURPOSE Circulating tumor DNA (ctDNA) analyses allow for postoperative risk stratification
in patients with curatively treated colon and breast cancers. Use of ctDNA in …

[HTML][HTML] Strategies for improving detection of circulating tumor DNA using next generation sequencing

R Tébar-Martínez, J Martín-Arana… - Cancer Treatment …, 2023 - Elsevier
Cancer has become a global health issue and liquid biopsy has emerged as a non-invasive
tool for various applications. In cancer, circulating tumor DNA (ctDNA) can be detected from …

Circulating tumor DNA predicts outcome in metastatic gastroesophageal cancer

MJM van Velzen, A Creemers, T van den Ende… - Gastric Cancer, 2022 - Springer
Abstract Background Circulating tumor DNA (ctDNA) has predictive and prognostic value in
localized and metastatic cancer. This study analyzed the prognostic value of baseline and …

[HTML][HTML] Liquid Biopsies: Emerging role and clinical applications in solid tumours

S Sisodiya, V Kasherwal, A Khan, B Roy, A Goel… - Translational …, 2023 - Elsevier
Late detection and lack of precision diagnostics are the major challenges in cancer
prevention and management. Biomarker discovery in specific cancers, especially at the pre …

Validation of Lung EpiCheck, a novel methylation-based blood assay, for the detection of lung cancer in European and Chinese high-risk individuals

M Gaga, J Chorostowska-Wynimko… - European …, 2021 - Eur Respiratory Soc
Aim Lung cancer screening reduces mortality. We aim to validate the performance of Lung
EpiCheck, a six-marker panel methylation-based plasma test, in the detection of lung cancer …

Circulating tumor DNA-based disease monitoring of patients with locally advanced esophageal cancer

LSM Hofste, MJ Geerlings, D von Rhein, SH Tolmeijer… - Cancers, 2022 - mdpi.com
Simple Summary The standard of care for patients diagnosed with locally advanced
esophageal cancer is neoadjuvant chemoradiotherapy followed by surgery. There is a high …

Tumor burden monitoring with circulating tumor DNA during treatment in patients with esophageal squamous cell carcinoma

Y Morimoto, S Matsuda, H Kawakubo… - Annals of surgical …, 2023 - Springer
Background To guide appropriate treatment strategy, an accurate tumor monitoring modality
that reflects tumor burden during neoadjuvant treatment is required for esophageal …

Total neoadjuvant therapy in oesophageal and gastro-oesophageal junctional adenocarcinoma

HA Clements, TJ Underwood, RD Petty - British Journal of Cancer, 2024 - nature.com
Adenocarcinoma of the oesophagus and gastro-oesophageal junction represent a large
burden of cancer death in the Western World with an increasing incidence. In the past two …