Targeted delivery of therapeutic molecules into cancer cells is considered as a promising
strategy to tackle cancer. Antibody–drug conjugates (ADCs), in which a monoclonal …

Multiple, site-specific protein conjugation is increasingly attractive for the generation of
antibody–drug conjugates (ADCs). As it is important to control the number and position of …

Targeted therapy using specific monoclonal antibodies (mAbs) conjugated to
chemotherapeutic agents or toxins has become one of the top priorities in cancer therapy …

Rituximab is a chimeric monoclonal antibody directed against B-lymphocyte specific antigen
CD20, which is used for the treatment of B-cell malignancies. However, the effectiveness of …

Herein, an advanced bioconjugation technique to synthesize hybrid polymer‐antibody
nanoprobes tailored for fluorescent cell barcoding in flow cytometry‐based …

Pretargeting is a promising strategy to reach high imaging contrast in a shorter time than by
targeting with directly radiolabeled monoclonal antibodies (mAbs). One of problems in …

We compared different biofunctionalization strategies for immobilizing trastuzumab, an IgG
targeting the HER2 biomarker, onto 100 nm spherical gold nanoparticles because of the E/K …

Background Although hen's egg allergy is more prevalent in children, up to 0.6% of adults
from different European countries suffer from a persistent or newly onset hen's egg allergy …

Conventional dried droplet (DD) methods show poor reproducibility in matrix-assisted laser
desorption/ionization mass spectrometry (MALDI-MS) due to the frequent induction of a …

Introduction: Trastuzumab is a common treatment for HER2-positive breast cancer.
Trastuzumab exerts its effect through inhibiting the intracellular signaling pathway induced …