Whoonga: Potential Recreational Use of HIV Antiretroviral Medication in South Africa

DJ Grelotti, EF Closson, JA Smit, Z Mabude… - AIDS and Behavior, 2014 - Springer
Whoonga is a drug cocktail in South Africa rumored to contain illicit drugs and HIV
antiretroviral (ARV) medication. Although its use may adversely impact adherence to HIV …

Universal antiretroviral therapy for HIV infection: should US treatment guidelines be applied to resource-limited settings?

JE Gallant, SH Mehta, J Sugarman - Clinical infectious diseases, 2013 - academic.oup.com
US treatment guidelines now recommend antiretroviral therapy (ART) for all persons
infected with human immunodeficiency virus (HIV), regardless of CD4 count, both for the …

HIV-1 disease progression and drug resistance mutations among children on first-line antiretroviral therapy in Ethiopia

Y Getaneh, F Getnet, F Ning, A Rashid, L Liao, F Yi… - Biomedicines, 2023 - mdpi.com
Background: High rates of disease progression and HIV drug resistance (HIVDR) among
adults taking highly active antiretroviral treatment (HAART) in Sub-Saharan Africa were …

HIV virological failure and drug resistance in a cohort of Tanzanian HIV-infected adults

C Hawkins, N Ulenga, E Liu, S Aboud… - Journal of …, 2016 - academic.oup.com
Objectives There are few data on ART failure rates and drug resistance from Tanzania,
where there is a wide diversity of non-B HIV subtypes. We assessed rates and predictors of …

Impact of human immunodeficiency virus type-1 sequence diversity on antiretroviral therapy outcomes

A Langs-Barlow, E Paintsil - Viruses, 2014 - mdpi.com
Worldwide circulating HIV-1 genomes show extensive variation represented by different
subtypes, polymorphisms and drug-resistant strains. Reports on the impact of sequence …

HIV-genetic diversity and drug resistance transmission clusters in Gondar, Northern Ethiopia, 2003-2013

DA Arimide, A Abebe, Y Kebede, F Adugna, T Tilahun… - PloS one, 2018 - journals.plos.org
Background The HIV-1 epidemic in Ethiopia has been shown to be dominated by two
phylogenetically distinct subtype C clades, the Ethiopian (C'-ET) and East African (C-EA) …

Magnitude and correlates of virological failure among adult HIV patients receiving PI based second line ART regimens in north western Tanzania; a case control study

DW Gunda, SB Kilonzo, T Mtaki, DM Bernard… - BMC infectious …, 2019 - Springer
Background With a growing access to free ART, switching of ART to second line regimen
has also become common following failure of first line ART regimens. Patients failing on first …

Sharp increase in rates of HIV transmitted drug resistance at antenatal clinics in Botswana demonstrates the need for routine surveillance

CF Rowley, IJ MacLeod, D Maruapula… - Journal of …, 2016 - academic.oup.com
Objectives The aim of the study was to evaluate for the presence of drug resistance to HIV
medications in treatment-naive individuals in Botswana. Methods Two different populations …

Primary resistance against integrase strand transfer inhibitors in integrase strand transfer inhibitor-naive patients failing first-and second-line ART in Tanzania

S Henerico, E Lyimo, AN Makubi… - Journal of …, 2022 - academic.oup.com
Abstract Introduction Sub-Saharan African countries are introducing integrase strand
transfer inhibitors (INSTIs) in their ART programmes as the preferred first-line regimen, and …

Brief report: impact of early antiretroviral therapy on the performance of HIV rapid tests and HIV incidence assays

JM Fogel, E Piwowar-Manning… - JAIDS Journal of …, 2017 - journals.lww.com
Background: Antiretroviral therapy (ART) can downregulate antibody responses to HIV
infection. We evaluated the impact of early vs. delayed ART on the performance of HIV …