Neurotransmitter systems have been long recognized as important targets of the
developmental actions of alcohol (ie, ethanol). Short-and long-term effects of ethanol on …

Background Fetal alcohol exposure is a leading cause of preventable birth defects, yet
drinking during pregnancy remains prevalent worldwide. Studies suggest that activation of …

Developmental ethanol exposure damages the hippocampus, causing long-lasting learning
and memory deficits. Synaptic plasticity mechanisms (eg, long-term potentiation [LTP]) …

Background Prenatal alcohol exposure (PAE) induces a wide range of neurodevelopmental
disabilities that are grouped under the term 'fetal alcohol spectrum disorders'(FASD). The …

Fetal alcohol spectrum disorders are often associated with structural and functional
hippocampal abnormalities, leading to long-lasting learning and memory deficits. The …

Prenatal alcohol exposure (PAE) affects neuronal networks and brain development causing
a range of physical, cognitive and behavioural disorders in newborns that persist into …

Neurosteroids (NS) are well known to exert modulatory effects on ionotropic receptors.
Recent findings indicate that NS could also act as important factors during development. In …

Long-term alcohol intake may cause nerve cell apoptosis and induce various
encephalopathies. Previously, we have shown that the expression of Na+/Ca 2+ exchanger …

Microglia undergo maturation during the third trimester of human development (equivalent to
the first 1–2 weeks of postnatal life in rodents), during which these cells may be particularly …

In light of the adverse reports of Bisphenol A (BPA) on reproduction and considering the
pivotal role played by the steroid receptors (SRs) and their coregulators in male …