A major feature of neurodegeneration is disruption of central nervous system homeostasis,
during which microglia play diverse roles. In the central nervous system, microglia serve as …

The role of neuroinflammation and the adaptive immune system in PD (Parkinson's disease)
has been the subject of intense investigation in recent years, both in animal models of …

Serpina3n is a secretory serine protease inhibitor belonging to clade “a” exhibiting unique
structural and physiological characteristics, playing significant roles ranging from …

Background Multiple sclerosis (MS) is an autoimmune inflammatory and neurodegenerative
disease of the central nervous system (CNS). It is widely accepted that inflammatory cells …

Neuropathological diagnosis of neurodegenerative dementias evolved by adapting the
results of neuroanatomy, biochemistry, and cellular and molecular biology. Milestone …

Symptoms in the urogenital organs are common in multiple system atrophy (MSA), also in
the years preceding the MSA diagnosis. It is unknown how MSA is triggered and these …

The development of disease-modifying therapies (DMTs) for neurological disorders is an
important goal in modern neurology, and the associated challenges are similar in many …

Clinicians involved with different aspects of the care of persons with multiple sclerosis (MS)
and scientists with expertise on clinical and imaging techniques convened in Dallas, TX …

Experimental autoimmune encephalomyelitis (EAE) is the most used animal model of
multiple sclerosis (MS) for the development of new therapies. Dopamine receptors can …

Introduction Our study aimed to evaluate whether assessing α-synuclein expression levels
in blood samples could provide a reliable and straightforward alternative to existing …