Virus-like particles: Revolutionary platforms for developing vaccines against emerging infectious diseases

H Tariq, S Batool, S Asif, M Ali, BH Abbasi - Frontiers in microbiology, 2022 - frontiersin.org
Virus-like particles (VLPs) are nanostructures that possess diverse applications in
therapeutics, immunization, and diagnostics. With the recent advancements in biomedical …

Materials engineering for immunomodulation

JA Hubbell, SN Thomas, MA Swartz - Nature, 2009 - nature.com
The engineering of materials that can modulate the immune system is an emerging field that
is developing alongside immunology. For therapeutic ends such as vaccine development …

Nanocarriers for cancer nano-immunotherapy

I Rana, J Oh, J Baig, JH Moon, S Son, J Nam - Drug Delivery and …, 2023 - Springer
The host immune system possesses an intrinsic ability to target and kill cancer cells in a
specific and adaptable manner that can be further enhanced by cancer immunotherapy …

Viral nanoparticles and virus‐like particles: platforms for contemporary vaccine design

EM Plummer, M Manchester - Wiley Interdisciplinary Reviews …, 2011 - Wiley Online Library
Current vaccines that provide protection against infectious diseases have primarily relied on
attenuated or inactivated pathogens. Virus‐like particles (VLPs), comprised of capsid …

Improvement of different vaccine delivery systems for cancer therapy

A Bolhassani, S Safaiyan, S Rafati - Molecular cancer, 2011 - Springer
Cancer vaccines are the promising tools in the hands of the clinical oncologist. Many tumor-
associated antigens are excellent targets for immune therapy and vaccine design. Optimally …

Current status of COVID‐19 (pre) clinical vaccine development

T Ye, Z Zhong, A García‐Sastre… - Angewandte Chemie …, 2020 - Wiley Online Library
The current COVID‐19 pandemic has a tremendous impact on daily life world‐wide. Despite
the ability to dampen the spread of SARS‐CoV‐2, the causative agent of the diseases …

Principles of vaccine design—lessons from nature

F Zepp - Vaccine, 2010 - Elsevier
Microbial pathogens have developed complex and efficient ways of counteracting and
evading innate and adaptive immune mechanisms. The strategies used by pathogens …

Vaccine process technology

JO Josefsberg, B Buckland - Biotechnology and bioengineering, 2012 - Wiley Online Library
The evolution of vaccines (eg, live attenuated, recombinant) and vaccine production
methods (eg, in ovo, cell culture) are intimately tied to each other. As vaccine technology has …

Different applications of virus‐like particles in biology and medicine: vaccination and delivery systems

Z Shirbaghaee, A Bolhassani - Biopolymers, 2016 - Wiley Online Library
Virus‐like particles (VLPs) mimic the whole construct of virus particles devoid of viral
genome as used in subunit vaccine design. VLPs can elicit efficient protective immunity as …

Nanovaccines for cancer immunotherapy

Y Zhang, S Lin, XY Wang, G Zhu - … Reviews: Nanomedicine and …, 2019 - Wiley Online Library
The past few decades have witnessed the booming field of cancer immunotherapy. Cancer
therapeutic vaccines, either alone or in combination with other immunotherapies such as …