Anemia is a common hematological disorder that affects 12% of the community-dwelling
population, 40% of hospitalized patients, and 47% of nursing home residents. Our …

Background Chronic kidney disease (CKD) and end-stage renal disease (ESKD) are
significant global health challenges associated with progressive kidney dysfunction and …

The α-Klotho protein (hereafter Klotho) is an obligate coreceptor for fibroblast growth factor
23 (FGF23). It is produced in the kidneys, brain and other sites. Klotho insufficiency causes …

Aging comes with the loss of muscle and bone mass, leading to a condition known as
osteosarcopenia. Circulating, cellular, and tissue biomarkers research for osteosarcopenia …

Xanthine oxidase (XO) plays a critical role in purine catabolism, catalyzing the conversion of
hypoxanthine to xanthine and xanthine to uric acid, contributing to superoxide anion …

The data reviewed here highlight the need for interdisciplinary collaboration between
nephrologists and neurologists in the care of patients with CKD at risk of cognitive …

ندــب یاه هاگتــسد رتــشيب رــب یدــيفم تارــثا یرــيپ دــض ريــسکا کــی ناوــنع هب یوــتولک:
هــمدقم زا یرايــسب رد وــتولک دــيفم تارــثا رــب یــنبم یداــیز تاــشرازگ رــيخا هــهد ود رد. دراد …‎

Identifying readily implementable methods that can effectively counteract aging is urgently
needed for tackling age-related degenerative disorders. Here, we conducted functional …

Introduction: Klotho, an elixir of life, beneficially affects several bodily systems, including the
brain. During the past two decades, positive effects of klotho in systemic and …

Abstract The Sirtuins 1-7 family and Klotho (KL), Forkhead box protein O1 (FOXO1),
telomerase reverse transcriptase (TERT), tumor suppressor p53 (TP53) and growth …