[HTML][HTML] Application of targeted maximum likelihood estimation in public health and epidemiological studies: a systematic review
Purpose The targeted maximum likelihood estimation (TMLE) statistical data analysis
framework integrates machine learning, statistical theory, and statistical inference to provide …
framework integrates machine learning, statistical theory, and statistical inference to provide …
[HTML][HTML] Beyond the single-outcome approach: A comparison of outcome-wide analysis methods for exposome research
A Anguita-Ruiz, I Amine, N Stratakis, L Maitre… - Environment …, 2023 - Elsevier
Outcome-wide analysis can offer several benefits, including increased power to detect weak
signals and the ability to identify exposures with multiple effects on health, which may be …
signals and the ability to identify exposures with multiple effects on health, which may be …