Can atmospheric pollution be considered a co-factor in extremely high level of SARS-CoV-2 lethality in Northern Italy?
E Conticini, B Frediani, D Caro - Environmental pollution, 2020 - Elsevier
This paper investigates the correlation between the high level of Severe Acute Respiratory
Syndrome CoronaVirus 2 (SARS-CoV-2) lethality and the atmospheric pollution in Northern …
Syndrome CoronaVirus 2 (SARS-CoV-2) lethality and the atmospheric pollution in Northern …
miRNA-mediated control of B cell responses in immunity and SLE
SL Schell, ZSM Rahman - Frontiers in immunology, 2021 - frontiersin.org
Loss of B cell tolerance is central to autoimmune diseases such as systemic lupus
erythematosus (SLE). As such, the mechanisms involved in B cell development, maturation …
erythematosus (SLE). As such, the mechanisms involved in B cell development, maturation …
Mechanisms of environment-induced autoimmunity
KM Pollard, DM Cauvi, JM Mayeux… - Annual review of …, 2021 - annualreviews.org
Although numerous environmental exposures have been suggested as triggers for
preclinical autoimmunity, only a few have been confidently linked to autoimmune diseases …
preclinical autoimmunity, only a few have been confidently linked to autoimmune diseases …
Systemic lupus erythematosus as a genetic disease
ITW Harley, AH Sawalha - Clinical Immunology, 2022 - Elsevier
Systemic lupus erythematosus is the prototypical systemic autoimmune disease, as it is
characterized both by protean multi-organ system manifestations and by the uniform …
characterized both by protean multi-organ system manifestations and by the uniform …
Air pollution, genetic susceptibility, and risk of incident systemic lupus erythematosus: a prospective cohort study
M Xing, Y Ma, F Cui, D Li, J Wang, L Tang… - Arthritis & …, 2024 - Wiley Online Library
Objective There are few existing studies that investigate the risk of systemic lupus
erythematosus (SLE) associated with long‐term exposure to air pollutants. This study aimed …
erythematosus (SLE) associated with long‐term exposure to air pollutants. This study aimed …
Dermatologic manifestations, histologic features and disease progression among cutaneous lupus erythematosus subtypes: a prospective observational study in …
K Chanprapaph, J Tankunakorn, P Suchonwanit… - Dermatology and …, 2021 - Springer
Introduction Cutaneous manifestations are central to the primary diagnosis of systemic lupus
erythematosus (SLE). However, information on the clinical, histopathologic, and direct …
erythematosus (SLE). However, information on the clinical, histopathologic, and direct …
Dietary docosahexaenoic acid prevents silica-induced development of pulmonary ectopic germinal centers and glomerulonephritis in the lupus-prone NZBWF1 …
MA Bates, P Akbari, KN Gilley, JG Wagner… - Frontiers in …, 2018 - frontiersin.org
Ectopic lymphoid structures (ELS) consist of B-cell and T-cell aggregates that are initiated de
novo in inflamed tissues outside of secondary lymphoid organs. When organized within …
novo in inflamed tissues outside of secondary lymphoid organs. When organized within …
UHRF1 downregulation promotes T follicular helper cell differentiation by increasing BCL6 expression in SLE
L Liu, L Hu, L Yang, S Jia, P Du, X Min, J Wu, H Wu… - Clinical …, 2021 - Springer
Background Transcription factor B cell lymphoma 6 (BCL6) is a master regulator of T
follicular helper (Tfh) cells, which play a crucial role in the pathogenesis of systemic lupus …
follicular helper (Tfh) cells, which play a crucial role in the pathogenesis of systemic lupus …
Lipopolysaccharide-enhanced responses against aryl hydrocarbon receptor in FcgRIIb-deficient macrophages, a profound impact of an environmental toxin on a …
K Udompornpitak, T Bhunyakarnjanarat… - International journal of …, 2021 - mdpi.com
Fc gamma receptor IIb (FcgRIIb) is the only inhibitory-FcgR in the FcgR family, and FcgRIIb-
deficient (FcgRIIb−/−) mice develop a lupus-like condition with hyper-responsiveness …
deficient (FcgRIIb−/−) mice develop a lupus-like condition with hyper-responsiveness …
Early and short-term interventions in the gut microbiota affects lupus severity, progression, and treatment in MRL/lpr mice
Y Zhang, Q Liu, Y Yu, M Wang, C Wen… - Frontiers in Microbiology, 2020 - frontiersin.org
There have been attempts to reveal the possible associations between systemic lupus
erythematosus (SLE) and gut microbiota. Using MRL/lpr mice, this study was performed to …
erythematosus (SLE) and gut microbiota. Using MRL/lpr mice, this study was performed to …