Microfluidics for understanding model organisms
New microfluidic systems for whole organism analysis and experimentation are catalyzing
biological breakthroughs across many fields, from human health to fundamental biology …
biological breakthroughs across many fields, from human health to fundamental biology …
Fly Me to the Micron: Microtechnologies for Drosophila Research
Multicellular model organisms, such as Drosophila melanogaster (fruit fly), are frequently
used in a myriad of biological research studies due to their biological significance and …
used in a myriad of biological research studies due to their biological significance and …
Fly-on-a-Chip: Microfluidics for Drosophila melanogaster Studies
The fruit fly or Drosophila melanogaster has been used as a promising model organism in
genetics, developmental and behavioral studies as well as in the fields of neuroscience …
genetics, developmental and behavioral studies as well as in the fields of neuroscience …
Immobilizing second-instar Drosophila larvae for imaging and surgery using the larva chip
LJ Smithson, TJ Waller… - Cold Spring Harbor …, 2024 - cshprotocols.cshlp.org
The simple body plan and semitranslucent cuticle of the Drosophila larva allow for imaging
of structures close to the body wall within intact animals. These include sensory neurons …
of structures close to the body wall within intact animals. These include sensory neurons …
Microfluidics for mechanobiology of model organisms
Mechanical stimuli play a critical role in organ development, tissue homeostasis, and
disease. Understanding how mechanical signals are processed in multicellular model …
disease. Understanding how mechanical signals are processed in multicellular model …
A minimal constraint device for imaging nuclei in live Drosophila contractile larval muscles reveals novel nuclear mechanical dynamics
Muscle contractions produce reiterated cytoplasmic mechanical variations, which potentially
influence nuclear mechanotransduction, however information regarding the dynamics of …
influence nuclear mechanotransduction, however information regarding the dynamics of …
Tools to reverse-engineer multicellular systems: case studies using the fruit fly
Reverse-engineering how complex multicellular systems develop and function is a grand
challenge for systems bioengineers. This challenge has motivated the creation of a suite of …
challenge for systems bioengineers. This challenge has motivated the creation of a suite of …
LarvaSPA, a method for mounting Drosophila larva for long-term time-lapse imaging
H Ji, C Han - Journal of visualized experiments: JoVE, 2020 - pmc.ncbi.nlm.nih.gov
Live imaging is a valuable approach for investigating cell biology questions. The Drosophila
larva is particularly suited for in vivo live imaging because the larval body wall and most …
larva is particularly suited for in vivo live imaging because the larval body wall and most …
Bending Drosophila larva using a microfluidic device enables imaging of its brain and nervous system at single neuronal resolution
Single neuronal imaging of a fully intact Drosophila larva is a difficult challenge for
neurosciences due to the robust digging/burrowing behaviour of the Drosophila larva and …
neurosciences due to the robust digging/burrowing behaviour of the Drosophila larva and …
微流控芯片在昆虫研究中的应用.
欧英琪， 薛堃 - Chinese Journal of Applied Entomology, 2022 - search.ebscohost.com
摘要与昆虫学相关的研究是生命科学最早的研究领域之一, 在害虫防治, 资源昆虫利用和模式
生物(例如黑腹果蝇Drosophila melanogaster) 等研究领域有重要意义. 微流控芯片(Microfluidic …
生物(例如黑腹果蝇Drosophila melanogaster) 等研究领域有重要意义. 微流控芯片(Microfluidic …