Seventy-six 2-phenylbenzimidazole derivatives were synthesized and evaluated in cell-
based assays for cytotoxicity and antiviral activity against a panel of 10 RNA and DNA …

Bovine viral diarrhea virus (BVDV) was first reported 75 years ago and remains a source of
major financial and production losses in the North American cattle industry. Currently …

Multi-target EGFR, VEGFR-2 and PDGFR inhibitors are highly useful anticancer agents with
improved therapeutic efficacies. In this work, we used two virtual screening methods, support …

The pestiviruses, bovine viral diarrhea virus (BVDV), classical swine fever (CSFV) and
border disease virus, are important livestock pathogens in many countries, but current …

Owing to the growing need for antifungal agents, we synthesized a new series 2-((5-(4-(5-
substituted-1 H-benzimidazol-2-yl) phenyl)-4-substituted-4 H-1, 2, 4-triazol-3-yl) thio)-1 …

A robust cell-free platform technology, ribosome display in combination with cloning,
expression, and purification was utilized to develop single chain Fragment variable (scFv) …

An understanding of the interaction between the antibody and its targeted antigen and
knowing of the epitopes are critical for the development of monoclonal antibody drugs …

The development of potent non-nucleoside inhibitors (NNIs) could be an alternate strategy
to combating infectious bovine viral diarrhea virus (BVDV), other than the traditional …

Linear aromatic N-tricyclic compounds with promising antiviral activity and minimal
cytotoxicity were prepared and analyzed in the last years. Specifically, the pyrido [2, 3-g] …

To explore the hydrophobic binding region of the σ1 receptor protein, regioisomeric
spirocyclic thiophenes 9–11 were developed as versatile building blocks. Regioselective α …