Serial block face scanning electron microscopy in cell biology: Applications and technology
D Smith, T Starborg - Tissue and Cell, 2019 - Elsevier
Three-dimensional electron microscopy (3DEM) is an imaging field containing several
powerful modalities such as serial section transmission electron microscopy and electron …
powerful modalities such as serial section transmission electron microscopy and electron …
Multi-scale computational modeling of spatial calcium handling from nanodomain to whole-heart: Overview and perspectives
Regulation of intracellular calcium is a critical component of cardiac electrophysiology and
excitation-contraction coupling. The calcium spark, the fundamental element of the …
excitation-contraction coupling. The calcium spark, the fundamental element of the …
Diesel-derived PM2.5 induces impairment of cardiac movement followed by mitochondria dysfunction in cardiomyocytes
Particulate matter (PM) in polluted air can be exposed to the human body through inhalation,
ingestion, and skin contact, accumulating in various organs throughout the body. Organ …
ingestion, and skin contact, accumulating in various organs throughout the body. Organ …
EM-stellar: benchmarking deep learning for electron microscopy image segmentation
Motivation The inherent low contrast of electron microscopy (EM) datasets presents a
significant challenge for rapid segmentation of cellular ultrastructures from EM data. This …
significant challenge for rapid segmentation of cellular ultrastructures from EM data. This …
Electron microscopy of cardiac 3D nanodynamics: form, function, future
The 3D nanostructure of the heart, its dynamic deformation during cycles of contraction and
relaxation, and the effects of this deformation on cell function remain largely uncharted …
relaxation, and the effects of this deformation on cell function remain largely uncharted …
Insights on the impact of mitochondrial organisation on bioenergetics in high-resolution computational models of cardiac cell architecture
Recent electron microscopy data have revealed that cardiac mitochondria are not arranged
in crystalline columns but are organised with several mitochondria aggregated into columns …
in crystalline columns but are organised with several mitochondria aggregated into columns …
Quantification of myocyte disarray in human cardiac tissue
F Giardini, E Lazzeri, G Vitale, C Ferrantini… - Frontiers in …, 2021 - frontiersin.org
Proper three-dimensional (3D)-cardiomyocyte orientation is important for an effective
tension production in cardiac muscle. Cardiac diseases can cause severe remodeling …
tension production in cardiac muscle. Cardiac diseases can cause severe remodeling …
Comparison of detection method on malaria cell images
WA Mustafa, R Santiagoo, I Jamaluddin… - … Approach in Smart …, 2018 - ieeexplore.ieee.org
In the image analysis process, thresholding is one of the most important preprocessing
steps. Thresholding is a sort of picture division that separates protest apportioning a picture …
steps. Thresholding is a sort of picture division that separates protest apportioning a picture …
Three‐dimensional electron microscopy techniques for unravelling mitochondrial dysfunction in heart failure and identification of new pharmacological targets
HM Daghistani, BS Rajab… - British Journal of …, 2019 - Wiley Online Library
A hallmark of heart failure is mitochondrial dysfunction leading to a bioenergetics imbalance
in the myocardium. Consequently, there is much interest in targeting mitochondrial …
in the myocardium. Consequently, there is much interest in targeting mitochondrial …
CardioVinci: building blocks for virtual cardiac cells using deep learning
Advances in electron microscopy (EM) such as electron tomography and focused ion-beam
scanning electron microscopy provide unprecedented, three-dimensional views of cardiac …
scanning electron microscopy provide unprecedented, three-dimensional views of cardiac …