Multiple sclerosis (MS) is the commonest non‐traumatic disabling disease to affect young
adults. The incidence of MS is increasing worldwide, together with the socioeconomic …

The etiology of endemic rickets was discovered a century ago. Vitamin D is the precursor of
25-hydroxyvitamin D and other metabolites, including 1, 25 (OH) 2D, the ligand for the …

Vitamin D is an essential nutrient for bone health and may influence the risks of respiratory
illness, adverse pregnancy outcomes, and chronic diseases of adulthood. Because many …

Vitamin D deficiency is a candidate risk factor for a range of adverse health outcomes. In a
genome-wide association study of 25 hydroxyvitamin D (25OHD) concentration in 417,580 …

Genetic architecture describes the characteristics of genetic variation that are responsible for
heritable phenotypic variability. It depends on the number of genetic variants affecting a trait …

Vitamin D is a steroid hormone precursor that is associated with a range of human traits and
diseases. Previous GWAS of serum 25-hydroxyvitamin D concentrations have identified four …

Introduction Vitamin D deficiency is an important public health problem worldwide. Vitamin D
deficiency confers a significant risk for both skeletal and non-skeletal disorders and a …

Background Increased vitamin D levels, as reflected by 25-hydroxy vitamin D (25OHD)
measurements, have been proposed to protect against COVID-19 based on in vitro …

We aimed to increase our understanding of the genetic determinants of vitamin D levels by
undertaking a large-scale genome-wide association study (GWAS) of serum 25 …

Background Micronutrients play an essential role at every stage of the immune response,
and deficiencies can therefore lead to increased susceptibility to infections. Previous …