Bacillus Calmette-Guérin (BCG) therapy for bladder cancer: an update

S Guallar-Garrido, E Julián - ImmunoTargets and therapy, 2020 - Taylor & Francis
Physicians treating patients affected by nonmuscle-invasive bladder cancer (NMIBC) have
been in shock during the last six years since manufacturing restrictions on the production of …

Mycobacteria-based vaccines as immunotherapy for non-urological cancers

E Noguera-Ortega, S Guallar-Garrido, E Julián - Cancers, 2020 - mdpi.com
The arsenal against different types of cancers has increased impressively in the last decade.
The detailed knowledge of the tumor microenvironment enables it to be manipulated in …

Mycolicibacterium brumae is a Safe and Non-Toxic Immunomodulatory Agent for Cancer Treatment

M Bach-Griera, V Campo-Pérez, S Barbosa, S Traserra… - Vaccines, 2020 - mdpi.com
Intravesical Mycobacterium bovis Bacillus Calmette–Guérin (BCG) immunotherapy remains
the gold-standard treatment for non-muscle-invasive bladder cancer patients, even though …

Mycobacteria emulsified in olive oil-in-water trigger a robust immune response in bladder cancer treatment

E Noguera-Ortega, N Blanco-Cabra, RM Rabanal… - Scientific reports, 2016 - nature.com
The hydrophobic composition of mycobacterial cell walls leads to the formation of clumps
when attempting to resuspend mycobacteria in aqueous solutions. Such aggregation may …

Intravesical Mycobacterium brumae triggers both local and systemic immunotherapeutic responses against bladder cancer in mice

E Noguera-Ortega, RM Rabanal, E Gómez-Mora… - Scientific reports, 2018 - nature.com
The standard treatment for high-risk non-muscle invasive bladder cancer (BC) is the
intravesical administration of live Mycobacterium bovis BCG. Previous studies suggest …

Immunotherapy of Bacillus Calmette-Guérin by targeting macrophages against bladder cancer in a NOD/scid IL2Rg-/− mouse model

QL Tan, CY Zhou, L Cheng, M Luo… - Molecular …, 2020 - spandidos-publications.com
Bacillus Calmette-Guérin (BCG) is considered to be a successful biotherapy for treating
bladder cancer (BCa). However, the underlying mechanisms of BCG have not been …

Genomic analysis of Mycobacterium brumae sustains its nonpathogenic and immunogenic phenotype

C Renau-Mínguez, P Herrero-Abadía… - Frontiers in …, 2023 - frontiersin.org
Mycobacterium brumae is a rapid-growing, non-pathogenic Mycobacterium species,
originally isolated from environmental and human samples in Barcelona, Spain …

Bacteria-Derived Alternatives to Live Mycobacterium bovis Bacillus Calmette–Guerin for Nonmuscle Invasive Bladder Cancer Treatment

E Julián, E Noguera-Ortega - Microbial Infections and Cancer …, 2019 - taylorfrancis.com
The most successful immunotherapeutic treatment for nonmuscle invasive bladder cancer
(NMIBC) to date is the intravesical instillation of Mycobacterium bovis bacillus Calmette …

Mycobacteria-derived agents for the treatment of urological and renal cancers

E Noguera-Ortega, E Julián - Mycobacterium-Res Dev, 2018 - books.google.com
Mycobacteria are the unique group of bacteria that are currently used in antitumoral
immunotherapy. Specifically, intravesical instillation of viable cells of Mycobacterium bovis …

Draft Genome Sequence of Mycobacterium brumae ATCC 51384

G D'Auria, E Torrents, M Luquin, I Comas… - Genome …, 2016 - Am Soc Microbiol
Draft Genome Sequence of Mycobacterium brumae ATCC 51384 | Genome
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