Clinical potential of inclisiran for patients with a high risk of atherosclerotic cardiovascular disease

T Nishikido - Cardiovascular Diabetology, 2023 - Springer
Elevated low-density lipoprotein cholesterol (LDL-C) level is associated with an increased
risk of atherosclerotic cardiovascular disease. Although high-intensity lipid-lowering …

Rationale and design of SCOT-HEART 2 trial: CT angiography for the prevention of myocardial infarction

M McDermott, MN Meah, P Khaing, KL Wang… - Cardiovascular …, 2024 - jacc.org
Coronary artery disease continues to be the leading cause of death globally. Identifying
patients who are at risk of coronary artery disease remains a public health priority. At …

Statins are associated with increased insulin resistance and secretion

F Abbasi, C Lamendola, CS Harris… - … , and vascular biology, 2021 - Am Heart Assoc
Objective: Statin treatment reduces the risk of atherosclerotic cardiovascular disease but is
associated with a modest increased risk of type 2 diabetes, especially in those with insulin …

Cost effectiveness of inclisiran in atherosclerotic cardiovascular patients with elevated low-density lipoprotein cholesterol despite statin use: a threshold analysis

NR Desai, C Campbell, B Electricwala… - American Journal of …, 2022 - Springer
Background Inclisiran is a novel, cholesterol-lowering therapy, with a long duration of effect,
administered every 6 months (subcutaneously by a healthcare professional). In the ORION …

Assessment of beliefs and attitudes about statins posted on Twitter: a qualitative study

S Golder, K O'Connor, S Hennessy, R Gross… - JAMA network …, 2020 - jamanetwork.com
Importance Statins are prescribed to help lower cholesterol levels but have poor adherence
rates. Attitudes or beliefs toward medications are important to ascertain because they may …

Recent advances of cell membrane coated nanoparticles in treating cardiovascular disorders

C Zhu, J Ma, Z Ji, J Shen, Q Wang - Molecules, 2021 - mdpi.com
Cardiovascular diseases (CVDs) are the leading cause of death worldwide, causing
approximately 17.9 million deaths annually, an estimated 31% of all deaths, according to the …

An expert opinion paper on statin adherence and implementation of new lipid-lowering medications by the ESC Working Group on Cardiovascular Pharmacotherapy …

H Drexel, AJS Coats, I Spoletini, C Bilato… - European heart …, 2020 - academic.oup.com
Benefits and safety on statins have been well-established over 20 years of research. Despite
this, the vast majority of patients are not adequately treated and do not achieve the low …

Methods to improve medication adherence in patients with chronic inflammatory rheumatic diseases: a systematic literature review

M Lavielle, D Puyraimond-Zemmour, X Romand… - RMD open, 2018 - rmdopen.bmj.com
Objective Lack of adherence to treatment is frequent in chronic inflammatory rheumatic
diseases and is associated with poorer outcomes. The objective of this study was to …

Recommendations for the assessment and optimization of adherence to disease-modifying drugs in chronic inflammatory rheumatic diseases: A process based on …

L Gossec, A Molto, X Romand… - Joint Bone Spine, 2019 - Elsevier
Background Adherence to treatment is a key issue in chronic inflammatory rheumatic
diseases (CIRDs). Objective To develop recommendations to facilitate in daily practice, the …

[HTML][HTML] Thirty percent of children and young adults with familial hypercholesterolemia treated with statins have adherence issues

G Langslet, AK Johansen, MP Bogsrud… - American journal of …, 2021 - Elsevier
Objective To assess adherence to lipid lowering therapy (LLT), reasons for poor adherence,
and achievement of LDL-C treatment goals in children and young adults with familial …