Anticancer activity of curcumin and its analogues: preclinical and clinical studies

A Allegra, V Innao, S Russo, D Gerace… - Cancer …, 2017 - Taylor & Francis
Curcumin has been shown to have a wide variety of therapeutic effects, ranging from anti-
inflammatory, chemopreventive, anti-proliferative, and anti-metastatic. This review provides …

3-Chloro-3-methyl-2, 6-diarylpiperidin-4-ones as anti-cancer agents: synthesis, biological evaluation, molecular docking, and in silico ADMET prediction

A Ramalingam, N Mustafa, WJ Chng, M Medimagh… - Biomolecules, 2022 - mdpi.com
Piperidine pharmacophore-containing compounds have demonstrated therapeutic efficacy
against a range of diseases and are now being investigated in cancer. A series of 3-chloro-3 …

Critical assessment of the interaction between DNA and choline amino acid ionic liquids: evidences of multimodal binding and stability enhancement

DK Sahoo, S Jena, J Dutta, S Chakrabarty… - ACS Central …, 2018 - ACS Publications
Long-term storage and stability of DNA is of paramount importance in biomedical
applications. Ever since the emergence of ionic liquids (ILs) as alternate green solvents to …

Curcumin: From a controversial “panacea” to effective antineoplastic products

DB Xiang, KQ Zhang, YL Zeng, QZ Yan, Z Shi, QH Tuo… - Medicine, 2020 - journals.lww.com
Background Curcumin, a controversial “panacea,” has been broadly studied. Its bioactivities
including antioxidant, anti-inflammatory, and especially antineoplastic activities have been …

Synthesis, in-silico antiviral screening and in-vitro antibacterial screening of a novel chalcone derivatives

A Uniyal, BK Thakur, S Singh, J Gairolla… - Journal of the Indian …, 2023 - Elsevier
A new series of novel chalcones was synthesized and subjected to screening of theoretical
molecular and biological properties. For evaluating the theoretical molecular properties of …

Synthesis, conformational study and DFT analysis of novel nonlinear optically active 2r, 6c-diaryl-3t-methylpiperidin-4-one N-(2′-furoyl) hydrazones

V Meenatchi, SS Han - Journal of Molecular Structure, 2022 - Elsevier
A series of nonlinear optical (NLO) active 2-furoic acid hydrazide derivatives, 2r, 6c-diaryl-3t-
methylpiperidin-4-one N-(2′-furoyl) hydrazones (6–10), were synthesized. The structures of …

Synthesis, structural, photo-physical properties and DFT studies of some diarylheptanoids

RA Al-Balushi, IJ Al-Busaidi, H Al-Sharji… - Journal of Molecular …, 2022 - Elsevier
In the present work, we have described the structures, photo-physical properties and DFT
computations of some curcumin type diarylheptanoids (4a–c). These compounds were …

Interaction studies of cholinium-based ionic liquids with calf thymus DNA: spectrophotometric and computational methods

A Haque, I Khan, SI Hassan, MS Khan - Journal of Molecular Liquids, 2017 - Elsevier
Ionic liquids (ILs) are emerging class of low-melting solid which have potential to replace
conventional solvents. DNA is one of the primary targets of many synthetic agents which are …

Probing the interaction of an antiviral drug 8-methoxy-3-nitro-2-(4-methoxyphenyl)-2H-chromene (MNC) with DNA by experimental and computational approach

DK Sahoo, NP Mishra - Journal of Molecular Structure, 2024 - Elsevier
Deoxyribonucleic acid (DNA) is a major target in research pertaining to antiviral and
anticancer therapies since it is the principal genetic material that controls vital biological …

Molecular structure and ultrasound-assisted synthesis of the diazacrown derivative containing 2, 3, 4, 6-tetraaryl-γ piperidone

NT Dao, TT Do, TTT Pham, VTT Tran… - Mendeleev …, 2023 - Elsevier
A 14-membered azacrown ether, namely, 2 3, 2 5-diphenyl-7-tosyl-4, 10-dioxa-7-aza-2 (2, 6)-
piperidina-1 (2, 1), 3 (1, 2)-dinaphthalenacyclodecaphan-2 4-one, was successfully …