Exploring the level of agreement among different drug-drug interaction checkers: a comparative study on direct oral anticoagulants

M Carollo, S Crisafulli, F Ciccimarra… - Expert Opinion on …, 2024 - Taylor & Francis
ABSTRACT Background Direct oral anticoagulants (DOACs) may be involved in drug–drug
interactions (DDIs) potentially increasing the risk of adverse drug reactions. This study …

[HTML][HTML] Deciphering the Intricate Interplay in the Framework of Antibiotic-Drug Interactions: A Narrative Review

AF Radu, SG Bungau, RAC Aron, AG Tarce… - …, 2024 - pmc.ncbi.nlm.nih.gov
Drug interactions are a significant and integral part of the concept of medication-related
adverse events, whether referring to potential interactions or those currently observed in real …

Agreement of different drug-drug interaction checkers for proton pump inhibitors

M Carollo, S Crisafulli, M Selleri, L Piccoli… - JAMA Network …, 2024 - jamanetwork.com
Importance Proton pump inhibitors (PPIs) are a widely prescribed class of drugs, potentially
interacting with a large number of medicines, especially among older patients with …

Screening for severe drug-drug interactions in patients with multiple sclerosis: A comparison of three drug interaction databases

M Hecker, N Frahm, P Bachmann, JL Debus… - Frontiers in …, 2022 - frontiersin.org
Background: Patients with multiple sclerosis (MS) often undergo complex treatment
regimens, resulting in an increased risk of polypharmacy and potential drug-drug …

[HTML][HTML] Antiretroviral drug–drug interactions: A comparison of online drug interaction databases

EN Drwiega, ME Badowski… - Journal of Clinical …, 2022 - ncbi.nlm.nih.gov
What is known and objective: Antiretrovirals have a high drug interaction potential, which
can lead to increased toxicity and/or decreased efficacy. Multiple databases are available to …

Drug-drug interactions with oral anticoagulants: information consistency assessment of three commonly used online drug interactions databases in Switzerland

C Coumau, F Gaspar, J Terrier… - Frontiers in …, 2024 - frontiersin.org
Background: Toxicity or treatment failure related to drug-drug interactions (DDIs) are known
to significantly affect morbidity and hospitalization rates. Despite the availability of numerous …

Old drugs, new tricks: leveraging known compounds to disrupt coronavirus-induced cytokine storm

S Richman, C Lyman, A Nesterova, A Yuryev… - NPJ Systems Biology …, 2022 - nature.com
A major complication in COVID-19 infection consists in the onset of acute respiratory distress
fueled by a dysregulation of the host immune network that leads to a run-away cytokine …

Opinion paper on the systematic application of integrated bioinformatic tools to actuate routine precision medicine in poly-treated patients

M Borro, G Salerno, G Gentile… - Clinical Chemistry and …, 2023 - degruyter.com
Precision Medicine is a reality in selected medical areas, as oncology, or in excellent
healthcare structures, but it is still far to reach million patients who could benefit from this …

Using PIM-Taiwan, PRISCUS, and Beers criteria to assess potentially inappropriate medication use among older adults with 90-day rehospitalization: a population …

KP Hsieh, RY Huang, YH Yang, PS Ho… - Frontiers in …, 2023 - frontiersin.org
Background: Multimorbidity and polypharmacy increase the risk of hospitalization in older
adults receiving potentially inappropriate medication (PIM). The current study compared the …

[HTML][HTML] Shared decision-making for drug-drug interactions: formative evaluation of an anticoagulant drug interaction

AG Lumbreras, TJ Reese, G Del Fiol… - JMIR Formative …, 2022 - formative.jmir.org
Background: Warnings about drug-drug interactions (DDIs) between warfarin and
nonsteroidal anti-inflammatory drugs (NSAIDs) within electronic health records indicate …