The ADAMTS (A Disintegrin and Metalloproteinase with Thrombospondin motifs) family
Abstract The ADAMTS (A Disintegrin and Metalloproteinase with Thrombospondin motifs)
enzymes are secreted, multi-domain matrix-associated zinc metalloendopeptidases that …
enzymes are secreted, multi-domain matrix-associated zinc metalloendopeptidases that …
The evolution of extracellular matrix
S Özbek, PG Balasubramanian… - Molecular biology of …, 2010 - Am Soc Cell Biol
We present a perspective on the molecular evolution of the extracellular matrix (ECM) in
metazoa that draws on research publications and data from sequenced genomes and …
metazoa that draws on research publications and data from sequenced genomes and …
Patterns of gene duplication in the plant SKP1 gene family in angiosperms: evidence for multiple mechanisms of rapid gene birth
H Kong, LL Landherr, MW Frohlich… - The Plant …, 2007 - Wiley Online Library
Gene duplication plays important roles in organismal evolution, because duplicate genes
provide raw materials for the evolution of mechanisms controlling physiological and/or …
provide raw materials for the evolution of mechanisms controlling physiological and/or …
Regulation of ADAMTS proteases
KWJ Rose, N Taye, SZ Karoulias… - Frontiers in Molecular …, 2021 - frontiersin.org
A disintegrin and metalloprotease with thrombospondin type I motifs (ADAMTS) proteases
are secreted metalloproteinases that play key roles in the formation, homeostasis and …
are secreted metalloproteinases that play key roles in the formation, homeostasis and …
ADAMTS proteinases: a multi-domain, multi-functional family with roles in extracellular matrix turnover and arthritis
GC Jones, GP Riley - Arthritis research & therapy, 2005 - Springer
Members of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs)
family are known to influence development, angiogenesis, coagulation and progression of …
family are known to influence development, angiogenesis, coagulation and progression of …
Upregulation of a disintegrin and metalloproteinase with thrombospondin motifs-7 by miR-29 repression mediates vascular smooth muscle calcification
Y Du, C Gao, Z Liu, L Wang, B Liu, F He… - … , and vascular biology, 2012 - Am Heart Assoc
Objective—Vascular calcification significantly increases cardiovascular morbidity and
mortality. We recently reported that the deficiency of cartilage oligomeric matrix protein …
mortality. We recently reported that the deficiency of cartilage oligomeric matrix protein …
The evolution of the vertebrate metzincins; insights from Ciona intestinalis and Danio rerio
J Huxley-Jones, TK Clarke, C Beck, G Toubaris… - BMC evolutionary …, 2007 - Springer
Background The metzincins are a large gene superfamily of proteases characterized by the
presence of a zinc protease domain, and include the ADAM, ADAMTS, BMP1/TLL, meprin …
presence of a zinc protease domain, and include the ADAM, ADAMTS, BMP1/TLL, meprin …
ADAMTS proteoglycanases in the physiological and pathological central nervous system
Abstract ADAMTS-1,-4,-5 and-9 belong to 'a disintegrin and metalloproteinase with
thrombospondin motifs (ADAMTS)'family and more precisely to the proteoglycanases …
thrombospondin motifs (ADAMTS)'family and more precisely to the proteoglycanases …
Adhesion GPCRs in tumorigenesis
G Aust, D Zhu, EG Van Meir, L Xu - Adhesion G protein-coupled receptors …, 2016 - Springer
Graphical Abstract Abstract Alterations in the homeostasis of several adhesion GPCRs
(aGPCRs) have been observed in cancer. The main cellular functions regulated by aGPCRs …
(aGPCRs) have been observed in cancer. The main cellular functions regulated by aGPCRs …
Regulation of procollagen amino-propeptide processing during mouse embryogenesis by specialization of homologous ADAMTS proteases: insights on collagen …
Mutations in ADAMTS2, a procollagen amino-propeptidase, cause severe skin fragility,
designated as dermatosparaxis in animals, and a subtype of the Ehlers-Danlos syndrome …
designated as dermatosparaxis in animals, and a subtype of the Ehlers-Danlos syndrome …