Cerebral amyloid angiopathy and Alzheimer disease—one peptide, two pathways

SM Greenberg, BJ Bacskai… - Nature Reviews …, 2020 - nature.com
The shared role of amyloid-β (Aβ) deposition in cerebral amyloid angiopathy (CAA) and
Alzheimer disease (AD) is arguably the clearest instance of crosstalk between …

[HTML][HTML] Vascular cognitive impairment (VCI)

T Rundek, M Tolea, T Ariko, EA Fagerli, CJ Camargo - Neurotherapeutics, 2023 - Elsevier
Vascular cognitive impairment (VCI) is predominately caused by vascular risk factors and
cerebrovascular disease. VCI includes a broad spectrum of cognitive disorders, from mild …

Progression of cerebral amyloid angiopathy: a pathophysiological framework

EA Koemans, JP Chhatwal, SJ van Veluw… - The Lancet …, 2023 - thelancet.com
Cerebral amyloid angiopathy, which is defined by cerebrovascular deposition of amyloid β,
is a common age-related small vessel pathology associated with intracerebral haemorrhage …

Cerebral small vessel disease: from a focal to a global perspective

A Ter Telgte, EMC Van Leijsen, K Wiegertjes… - Nature Reviews …, 2018 - nature.com
Cerebral small vessel disease (SVD) is commonly observed on neuroimaging among
elderly individuals and is recognized as a major vascular contributor to dementia, cognitive …

Diagnosis of cerebral amyloid angiopathy: evolution of the Boston criteria

SM Greenberg, A Charidimou - Stroke, 2018 - Am Heart Assoc
492 Stroke February 2018 lobar hemorrhages required for probable CAA, or alternatively
preclude probable CAA if in deep territories. The rationale for counting all types of …

Vascular cognitive impairment

M Dichgans, D Leys - Circulation research, 2017 - Am Heart Assoc
Cerebrovascular disease typically manifests with stroke, cognitive impairment, or both.
Vascular cognitive impairment refers to all forms of cognitive disorder associated with …

Emerging concepts in sporadic cerebral amyloid angiopathy

A Charidimou, G Boulouis, ME Gurol, C Ayata… - Brain, 2017 - academic.oup.com
Sporadic cerebral amyloid angiopathy is a common, well-defined small vessel disease and
a largely untreatable cause of intracerebral haemorrhage and contributor to age-related …

Cerebral small vessel disease and vascular cognitive impairment: from diagnosis to management

MCZ Zotin, L Sveikata, A Viswanathan… - Current opinion in …, 2021 - journals.lww.com
SVD is the leading cause of VCI and is associated with substantial morbidity. Tackling
cardiovascular risk factors is currently the most effective approach to prevent cognitive …

The increasing impact of cerebral amyloid angiopathy: essential new insights for clinical practice

G Banerjee, R Carare, C Cordonnier… - Journal of Neurology …, 2017 - jnnp.bmj.com
Cerebral amyloid angiopathy (CAA) has never been more relevant. The last 5 years have
seen a rapid increase in publications and research in the field, with the development of new …

White matter hyperintensity patterns in cerebral amyloid angiopathy and hypertensive arteriopathy

A Charidimou, G Boulouis, K Haley, E Auriel… - Neurology, 2016 - AAN Enterprises
Objective: To identify different white matter hyperintensity (WMH) patterns between 2
hemorrhage-prone cerebral small vessel diseases (SVD): cerebral amyloid angiopathy …