Tissue engineering is approach of replacing or regeneration of biological functions of
tissues or organs by using combination of biomaterials, biomolecules and cells. Tissue …

Liver diseases can be caused by viral infection, metabolic disorder, alcohol consumption,
carcinoma or injury, chronically progressing to end-stage liver disease or rapidly resulting in …

Epithelial organ remodeling is a major contributing factor to worldwide death and disease,
costing healthcare systems billions of dollars every year. Despite this, most fundamental …

Bioartificial liver (BAL) system has become a promising alternative to traditional liver
transplantation in rescuing acute liver failure (ALF) patients. Herein, inspired by natural …

Whole organ engineering and cell‐based regenerative medicine approaches are being
investigated as potential therapeutic options for end‐stage liver failure. However, a major …

Acute liver failure (ALF) is a rapidly progressive disease with high morbidity and mortality
rates. Liver transplantation and artificial liver (AL) support systems, such as ALs and …

Liver diseases contribute markedly to the global burden of mortality and disease. The limited
organ disposal for orthotopic liver transplantation results in a continuing need for alternative …

Extracellular matrix (ECM) rigidity has important effects on cell behaviors and increases
sharply in liver fibrosis and cirrhosis. Hepatic blood flow is essential in maintaining …

Liver-like organoids that recapitulate the complex functions of the whole liver by combining
cells, scaffolds, and mechanical or chemical cues are becoming important models for …

The burden of liver diseases is increasing worldwide, accounting for two million deaths
annually. In the past decade, tremendous progress has been made in the basic and …