Principles governing locomotion in vertebrates: lessons from zebrafish

EM Berg, ER Björnfors, I Pallucchi, LD Picton… - Frontiers in neural …, 2018 - frontiersin.org
Locomotor behaviors are critical for survival and enable animals to navigate their
environment, find food and evade predators. The circuits in the brain and spinal cord that …

Dopamine: a parallel pathway for the modulation of spinal locomotor networks

SA Sharples, K Koblinger, JM Humphreys… - Frontiers in neural …, 2014 - frontiersin.org
The spinal cord contains networks of neurons that can produce locomotor patterns. To
readily respond to environmental conditions, these networks must be flexible yet at the same …

Whole-brain activity mapping onto a zebrafish brain atlas

O Randlett, CL Wee, EA Naumann, O Nnaemeka… - Nature …, 2015 - nature.com
In order to localize the neural circuits involved in generating behaviors, it is necessary to
assign activity onto anatomical maps of the nervous system. Using brain registration across …

Neurotoxicity of the Cu(OH)2 Nanopesticide through Perturbing Multiple Neurotransmitter Pathways in Developing Zebrafish

S Chen, Y Qin, X Ye, J Liu, X Yan, L Zhou… - Environmental …, 2023 - ACS Publications
The copper hydroxide [Cu (OH) 2] nanopesticide is an emerging agricultural chemical that
can negatively impact aquatic organisms. This study evaluated the behavioral changes of …

Multiple convergent hypothalamus–brainstem circuits drive defensive behavior

M Lovett-Barron, R Chen, S Bradbury… - Nature …, 2020 - nature.com
The hypothalamus is composed of many neuropeptidergic cell populations and directs
multiple survival behaviors, including defensive responses to threats. However, the …

ZebraZoom: an automated program for high-throughput behavioral analysis and categorization

O Mirat, JR Sternberg, KE Severi, C Wyart - Frontiers in neural circuits, 2013 - frontiersin.org
The zebrafish larva stands out as an emergent model organism for translational studies
involving gene or drug screening thanks to its size, genetics, and permeability. At the larval …

Norepinephrine is required to promote wakefulness and for hypocretin-induced arousal in zebrafish

C Singh, G Oikonomou, DA Prober - Elife, 2015 - elifesciences.org
Pharmacological studies in mammals suggest that norepinephrine (NE) plays an important
role in promoting arousal. However, the role of endogenous NE is unclear, with contradicting …

[HTML][HTML] Dopamine from the brain promotes spinal motor neuron generation during development and adult regeneration

MM Reimer, A Norris, J Ohnmacht, R Patani, Z Zhong… - Developmental cell, 2013 - cell.com
Coordinated development of brain stem and spinal target neurons is pivotal for the
emergence of a precisely functioning locomotor system. Signals that match the development …

Characterization of A11 neurons projecting to the spinal cord of mice

K Koblinger, T Füzesi, J Ejdrygiewicz, A Krajacic… - PloS one, 2014 - journals.plos.org
The hypothalamic A11 region has been identified in several species including rats, mice,
cats, monkeys, zebrafish, and humans as the primary source of descending dopamine (DA) …

Effects of low‐dose chlorpyrifos on neurobehavior and potential mechanisms: A review of studies in rodents, zebrafish, and Caenorhabditis elegans

MH Silva - Birth defects research, 2020 - Wiley Online Library
Objectives Exposure to chlorpyrifos (CPF), a neurotoxic insecticide, is implicated with
adverse neurodevelopmental effects in children through noncholinergic mechanisms …