Transferosomes as a transdermal drug delivery system: Dermal kinetics and recent developments

N Matharoo, H Mohd… - Wiley Interdisciplinary …, 2024 - Wiley Online Library
The development of innovative approaches to deliver medications has been growing now
for the last few decades and generates a growing interest in the dermatopharmaceutical …

Transfersome, an ultra-deformable lipid-based drug nanocarrier: an updated review with therapeutic applications

Simrah, A Hafeez, SA Usmani, MP Izhar - … -Schmiedeberg's Archives of …, 2024 - Springer
The application of nanotechnology with integration of chemical sciences is increasing
continuously in the management of diseases. The drug's physicochemical and …

Phytosomes as a plausible nano-delivery system for enhanced oral bioavailability and improved hepatoprotective activity of silymarin

RG Shriram, A Moin, HF Alotaibi, ES Khafagy… - Pharmaceuticals, 2022 - mdpi.com
Silymarin, a phyto-constituent derived from the plant Silybum marianum, has been widely
acknowledged for its hepatoprotective activities. Nevertheless, its clinical utility is adversely …

Tailoring of novel bile salt stabilized vesicles for enhanced transdermal delivery of simvastatin: a new therapeutic approach against inflammation

ES Khafagy, BK Almutairy, AS Abu Lila - Polymers, 2023 - mdpi.com
Simvastatin (SMV), a cholesterol-lowering agent, has antioxidant and anti-inflammatory
effects. Nevertheless, the oral use of SMV is linked with poor systemic bioavailability owing …

Development and optimization of erythromycin loaded transethosomes cinnamon oil based emulgel for antimicrobial efficiency

MH Abdallah, HA Elghamry, NE Khalifa, WMA Khojali… - Gels, 2023 - mdpi.com
Erythromycin (EM) is a macrolide antibiotic that is frequently used to treat skin bacterial
infections. It has a short half-life (1–1.5 h), instability in stomach pH, and a low oral …

Expanding the arsenal against diabetes mellitus via transdermal application of drug-loaded nanoparticles and microneedles: Recent advances and future …

PS Kumbhar, K Kolekar, S Nadaf, S Vishwas… - Journal of Drug Delivery …, 2024 - Elsevier
Diabetes mellitus (DM) is a metabolic disease marked by elevated blood glucose levels
brought on by either the destruction of the beta cells or increased resistance to insulin. The …

[HTML][HTML] Formulation optimization, in vitro and in vivo evaluation of niosomal nanocarriers for enhanced topical delivery of cetirizine

MF Aldawsari, ES Khafagy, EH Moglad… - Saudi Pharmaceutical …, 2023 - Elsevier
Cetirizine hydrochloride (CTZ), a second-generation anti-histaminic drug, has been recently
explored for its effectiveness in the treatment of alopecia. Niosomes are surfactant-based …

[HTML][HTML] Maximizing the Use of Ivermectin Transethosomal Cream in the Treatment of Scabies

MH Alyami, HS Alyami, AM Abdo, S A. Sabry… - Pharmaceutics, 2024 - mdpi.com
In an effort to tackle the skin reactions frequently observed with topical application of
ivermectin (IVM), a study was conducted to develop and optimize transethosomes (TESMs) …

Ginger extract-loaded sesame oil-based niosomal emulgel: quality by design to ameliorate anti-inflammatory activity

MH Abdallah, HA Elghamry, NE Khalifa, WMA Khojali… - Gels, 2022 - mdpi.com
Ginger, a natural plant belonging to the Zingeberaceae family, has been reported to have
reasonable anti-inflammatory effects. The current study aimed to examine ginger extract …

Optimization of Potential Nanoemulgels for Boosting Transdermal Glimepiride Delivery and Upgrading Its Anti-Diabetic Activity

MH Abdallah, AS Abu Lila, HM El-Nahas, TM Ibrahim - Gels, 2023 - mdpi.com
Transdermal drug delivery has been widely adopted as a plausible alternative to the oral
route of administration, especially for drugs with poor systemic bioavailability. The objective …