Direct‐acting antivirals for chronic hepatitis C

JC Jakobsen, EE Nielsen, J Feinberg… - Cochrane database …, 2017 - cochranelibrary.com
Background Millions of people worldwide suffer from hepatitis C, which can lead to severe
liver disease, liver cancer, and death. Direct‐acting antivirals (DAAs), eg sofosbuvir, are …

safety and tolerability of direct‐acting anti‐viral agents in the new era of hepatitis C therapy

D Banerjee, KR Reddy - Alimentary pharmacology & …, 2016 - Wiley Online Library
Background Direct‐acting anti‐virals (DAAs) licensed to treat chronic HCV infection have
revolutionised treatment algorithms by drastically mitigating side effects while enhancing …

HCV in Egypt, prevention, treatment and key barriers to elimination

M El Kassas, T Elbaz, A Elsharkawy… - Expert review of anti …, 2018 - Taylor & Francis
Introduction: Currently, direct-acting antivirals (DAAs) are considered the ideal choice for the
treatment of chronic HCV patients due to their proven efficacy (SVR> 90%), and minimal …

[PDF][PDF] Ginsenoside Rg3 restores hepatitis C virus–induced aberrant mitochondrial dynamics and inhibits virus propagation

SJ Kim, JY Jang, EJ Kim, EK Cho, DG Ahn, C Kim… - …, 2017 - Wiley Online Library
Hepatitis C virus (HCV) alters mitochondrial dynamics associated with persistent viral
infection and suppression of innate immunity. Mitochondrial dysfunction is also a pathologic …

Beyond a 'post-cure'world: Sketches for a new futurology of hepatitis C

K Seear, S Fraser, A Farrugia - International Journal of Drug Policy, 2021 - Elsevier
Australia's recent investment in, and optimism about, direct-acting antivirals to treat hepatitis
C brings with it the promise of new drug futures, including the possibility of a post-hepatitis C …

Hepatocellular carcinoma and hepatitis C virus treatments: The bold and the beautiful

W Abdelhamed, M El‐Kassas - Journal of Viral Hepatitis, 2023 - Wiley Online Library
The occurrence of hepatocellular carcinoma (HCC) is one of the most serious complications
of hepatitis C virus (HCV) infection. Recently, effective antiviral medications have made …

Improved (4 plus 2) rituximab protocol for severe cases of mixed cryoglobulinemia: a 6-year observational study

D Roccatello, S Sciascia, S Baldovino… - American Journal of …, 2016 - karger.com
Background: In a prospective, single-center open study, we evaluated the very long-term
effects of rituximab (RTX) administered to patients with severe mixed cryoglobulinemia (MC) …

Neutrophil‐to‐lymphocyte ratio predicts recurrence after radiofrequency ablation in hepatitis B virus infection

K Tajiri, H Baba, K Kawai, M Minemura… - Journal of …, 2016 - Wiley Online Library
Abstract Background and Aim: Radiofrequency ablation (RFA) is an established treatment
for small hepatocellular carcinoma (HCC) wherein non‐recurrence is essential for long‐term …

[HTML][HTML] Ursodeoxycholic acid in treatment of non-cholestatic liver diseases: a systematic review

J Reardon, T Hussaini, M Alsahafi… - Journal of clinical and …, 2016 - ncbi.nlm.nih.gov
Aims: To systematically evaluate the literature for evidence to support the use of bile acids in
non-cholestatic liver conditions. Methods: Searches were conducted on the databases of …

Safety of direct antiviral agents in the management of hepatitis C

M El Kassas, T Elbaz, E Hafez… - Expert opinion on drug …, 2016 - Taylor & Francis
Introduction: Hepatitis C virus is a hepatotropic virus that generally leads to chronic hepatitis
and various harmful sequelae. The lone standard of treatment has been pegylated interferon …