Self-healing injectable hydrogels for tissue regeneration

P Bertsch, M Diba, DJ Mooney… - Chemical …, 2022 - ACS Publications
Biomaterials with the ability to self-heal and recover their structural integrity offer many
advantages for applications in biomedicine. The past decade has witnessed the rapid …

PEG-based thermosensitive and biodegradable hydrogels

J Shi, L Yu, J Ding - Acta biomaterialia, 2021 - Elsevier
Injectable thermosensitive hydrogels are free-flowing polymer solutions at low or room
temperature, making them easy to encapsulate the therapeutic payload or cells via simply …

Exosomes‐loaded Electroconductive hydrogel synergistically promotes tissue repair after spinal cord injury via Immunoregulation and enhancement of myelinated …

L Fan, C Liu, X Chen, L Zheng, Y Zou, H Wen… - Advanced …, 2022 - Wiley Online Library
Electroconductive hydrogels are very attractive candidates for accelerated spinal cord injury
(SCI) repair because they match the electrical and mechanical properties of neural tissue …

[HTML][HTML] A reactive oxygen species-responsive hydrogel encapsulated with bone marrow derived stem cells promotes repair and regeneration of spinal cord injury

Z Li, T Zhao, J Ding, H Gu, Q Wang, Y Wang, D Zhang… - Bioactive materials, 2023 - Elsevier
Spinal cord injury (SCI) is an overwhelming and incurable disabling event accompanied by
complicated inflammation-related pathological processes, such as excessive reactive …

Transplantation of human mesenchymal stem-cell-derived exosomes immobilized in an adhesive hydrogel for effective treatment of spinal cord injury

L Li, Y Zhang, J Mu, J Chen, C Zhang, H Cao, J Gao - Nano letters, 2020 - ACS Publications
Spinal cord injury is among the most fatal diseases. The complicated inhibitory
microenvironment requires comprehensive mitigation. Exosomes derived from …

Light‐triggered in situ gelation to enable robust photodynamic‐immunotherapy by repeated stimulations

Z Meng, X Zhou, J Xu, X Han, Z Dong… - Advanced …, 2019 - Wiley Online Library
Photodynamic therapy (PDT) has shown the potential of triggering systemic antitumor
immune responses. However, while the oxygen‐deficient hypoxic tumor microenvironment …

Soft conducting polymer hydrogels cross-linked and doped by tannic acid for spinal cord injury repair

L Zhou, L Fan, X Yi, Z Zhou, C Liu, R Fu, C Dai… - Acs Nano, 2018 - ACS Publications
Mimicking soft tissue mechanical properties and the high conductivity required for electrical
transmission in the native spinal cord is critical in nerve tissue regeneration scaffold designs …

[HTML][HTML] An injectable, self-healing, electroconductive extracellular matrix-based hydrogel for enhancing tissue repair after traumatic spinal cord injury

Y Luo, L Fan, C Liu, H Wen, S Wang, P Guan, D Chen… - Bioactive materials, 2022 - Elsevier
Injectable biomaterial-based treatment is a promising strategy to enhance tissue repair after
traumatic spinal cord injury (SCI) by bridging cavity spaces. However, there are limited …

[HTML][HTML] Injectable hydrogels in central nervous system: Unique and novel platforms for promoting extracellular matrix remodeling and tissue engineering

E Hasanzadeh, A Seifalian, A Mellati, J Saremi… - Materials Today Bio, 2023 - Elsevier
Repairing central nervous system (CNS) is difficult due to the inability of neurons to recover
after damage. A clinically acceptable treatment to promote CNS functional recovery and …

A MnO2 Nanoparticle-Dotted Hydrogel Promotes Spinal Cord Repair via Regulating Reactive Oxygen Species Microenvironment and Synergizing with …

L Li, B Xiao, J Mu, Y Zhang, C Zhang, H Cao, R Chen… - ACS …, 2019 - ACS Publications
Spinal cord injury (SCI) is one of the most debilitating injuries, and transplantation of stem
cells in a scaffold is a promising strategy for treatment. However, stem cell treatment of SCI …