Abstract Treatment with nonsteroidal anti-inflammatory drugs (NSAIDs) is associated with
various side effects, including cardiovascular and hepatic disorders. Studies suggest that …

The development of in vitro models that recapitulate critical liver functions is essential for
accurate assessments of drug toxicity. Although liver organoids can be used for drug …

Liver tissue engineering approaches aim to support drug testing, assistance devices, or
transplantation. However, their suitability for clinical application remains unsatisfactory …

The rise of three-dimensional cell culture systems that provide in vivo-like environments for
pharmaco-toxicological models has prompted the need for simple and robust viability …

Hepatic steatosis (ie lipid accumulation) and steatohepatitis have been related to diverse
etiologic factors, including alcohol, obesity, environmental pollutants. However, no study has …

Oximes play an essential role in the therapy of organophosphorus compound (OP)
poisoning by reactivating inhibited acetylcholinesterase. Impairment of liver function was …

Rationale: While some non-steroidal anti-inflammatory drugs (NSAIDs) are reported to
induce hepatic steatosis, the molecular mechanisms are poorly understood. This study …

Ethanol is the most frequently psychoactive substance used in the world, leading to major
public health problems with several millions of deaths attributed to alcohol consumption …

Phenylselenenylzinc chloride (PhSeZnCl) is an air-stable selenolate, easily synthesizable
through oxidative insertion of elemental zinc into the Se-halogen bond of the commercially …

Nonsteroidal anti-inflammatory drug (NSAID) use is associated with adverse consequences,
including hepatic injury. The detrimental hepatotoxicity of diclofenac, a widely used NSAID …