Robustly uncovering the heterogeneity of neurodegenerative disease by using data-driven subtyping in neuroimaging: A review
Neurodegenerative diseases are associated with heterogeneity in genetics, pathology, and
clinical manifestation. Understanding this heterogeneity is particularly relevant for clinical …
clinical manifestation. Understanding this heterogeneity is particularly relevant for clinical …
[HTML][HTML] No phenotypic or genotypic evidence for a link between sleep duration and brain atrophy
Short sleep is held to cause poorer brain health, but is short sleep associated with higher
rates of brain structural decline? Analysing 8,153 longitudinal MRIs from 3,893 healthy …
rates of brain structural decline? Analysing 8,153 longitudinal MRIs from 3,893 healthy …
[HTML][HTML] Conceptualizing healthy cognitive aging: The role of time and variability
EA Rodrigues, S Moreno - Frontiers in Human Neuroscience, 2023 - frontiersin.org
The interest in healthy cognitive aging (HCA) has increased substantially over the past
decade. Researchers are interested in exploring how health can be promoted and cognitive …
decade. Researchers are interested in exploring how health can be promoted and cognitive …
Is short sleep bad for the brain? Brain structure and cognitive function in short sleepers
Many sleep less than recommended without experiencing daytime sleepiness. According to
prevailing views, short sleep increases risk of lower brain health and cognitive function …
prevailing views, short sleep increases risk of lower brain health and cognitive function …
[HTML][HTML] A Subtype Perspective on Cognitive Trajectories in Healthy Aging
Cognitive aging is a complex and dynamic process characterized by changes due to
genetics and environmental factors, including lifestyle choices and environmental exposure …
genetics and environmental factors, including lifestyle choices and environmental exposure …
[HTML][HTML] Grey-matter structure in cortical and limbic regions correlates with general cognitive ability in old age
According to the maintenance hypothesis (Nyberg et al., 2012), structural integrity of the
brain's grey matter helps to preserve cognitive functioning into old age. A corollary of this …
brain's grey matter helps to preserve cognitive functioning into old age. A corollary of this …
The theory of orchid and dandelion offers a new subtyping framework for cognitive aging
Sylvain Moreno, Emma Rodrigues, Faranak Farzan www. aging-us. com 6628 AGING
subtyping by extending the orchid and dandelion theory to the cognitive aging population …
subtyping by extending the orchid and dandelion theory to the cognitive aging population …
[HTML][HTML] Longitudinal change-change associations of cognition with cortical thickness and surface area
L Nyberg, M Andersson, A Lundquist - Aging Brain, 2023 - Elsevier
Age-related changes in cortical volumes are well established but relatively few studies
probed its constituents, surface area (SA) and thickness (TH). Here we analyzed 10-year, 3 …
probed its constituents, surface area (SA) and thickness (TH). Here we analyzed 10-year, 3 …
Aging Brain from a Lifespan Perspective
AM Fjell - 2024 - Springer
Research during the last two decades has shown that the brain undergoes continuous
changes throughout life, with substantial heterogeneity in age trajectories between regions …
changes throughout life, with substantial heterogeneity in age trajectories between regions …
Age-related constraints on the spatial geometry of the brain
Age-related structural brain changes may be better captured by assessing complex spatial
geometric differences rather than isolated changes to individual regions. We applied a novel …
geometric differences rather than isolated changes to individual regions. We applied a novel …