Ambient air pollution has been identified as one of the leading causes of global burden of
disease. The relationship between ambient air pollution exposure and risk of chronic kidney …

Chronic kidney disease (CKD), a global disease burden related to high rates of incidence
and mortality, manifests as progressive and irretrievable nephron loss and decreased …

Background APOL1 genotype has significant effects on kidney disease development and
progression that vary among specific causes of kidney disease, suggesting the presence of …

APOL1 kidney risk variants (RVs) were identified in 2010 as major drivers of glomerular,
tubulointerstitial, and renal microvascular disease in individuals with sub-Saharan African …

Apolipoprotein L1 (APOL1) high risk variants confer an increased risk for the development
and progression of kidney disease among individuals of recent African ancestry. Over the …

Cardiorenal syndrome encompasses a dynamic interplay between cardiovascular and
kidney disease, and its prevention requires careful examination of multiple predisposing …

Evidence on the effects of fine particulate matter (PM 2.5) constituents and sources on
kidney injury is limited. We designed a panel study with 4 repeated measurements to …

Two variant alleles of the gene APOL1, known as risk variants (RVs), are a major contributor
to kidney disease burden in those of African descent. The APOL1 protein contributes to …

Background Two coding risk variants in the Apo L1 gene (APOL1) underlie most of the
excess risk for kidney diseases in recent African ancestry patients. Strength and consistency …

Focal segmental glomerular sclerosis (FSGS) is a histological lesion characterized by
sclerosis in sections (segmental) of some glomeruli (focal) in association with podocyte …