Osteoarthritis year in review 2023: Epidemiology & therapy

AV Perruccio, JJ Young, JM Wilfong, JD Power… - Osteoarthritis and …, 2024 - Elsevier
Objective To highlight some important findings from osteoarthritis (OA) epidemiology and
therapy research undertaken over the past year. Methods Search of MEDLINE and EMBASE …

Mimicking antioxidases and Hyaluronan synthase: a zwitterionic nanozyme for Photothermal Therapy of Osteoarthritis

P Yu, Y Li, H Sun, H Zhang, H Kang, P Wang… - Advanced …, 2023 - Wiley Online Library
Restoring joint homeostasis is crucial for relieving osteoarthritis (OA). Current strategies are
limited to unilateral efforts in joint lubrication, inhibition of inflammation, free radicals …

Engineering hyaluronic acid for the development of new treatment strategies for osteoarthritis

YS Kim, F Guilak - International journal of molecular sciences, 2022 - mdpi.com
Osteoarthritis (OA) is a degenerative joint disease that is characterized by inflammation of
the joints, degradation of cartilage, and the remodeling of other joint tissues. Due to the …

Injectable MSC spheroid and microgel granular composites for engineering tissue

ND Caprio, MD Davidson, AC Daly… - Advanced …, 2024 - Wiley Online Library
Many cell types require direct cell–cell interactions for differentiation and function; yet, this
can be challenging to incorporate into 3‐dimensional (3D) structures for the engineering of …

2023 American College of Rheumatology and American Association of hip and knee surgeons clinical practice guideline for the optimal timing of elective hip or knee …

CP Hannon, SM Goodman, MS Austin, A Yates Jr… - The Journal of …, 2023 - Elsevier
Objective To develop evidence-based consensus recommendations for the optimal timing of
hip and knee arthroplasty to improve patient-important outcomes including, but not limited to …

Knee osteoarthritis: disease burden, available treatments, and emerging options

M Langworthy, V Dasa… - Therapeutic Advances in …, 2024 - journals.sagepub.com
Osteoarthritis (OA) is a prevalent condition that affects nearly 528 million people worldwide,
including 23% of the global population aged⩾ 40, and is characterized by progressive …

Current and novel therapeutics for articular cartilage repair and regeneration

B Cong, T Sun, Y Zhao, M Chen - Therapeutics and Clinical Risk …, 2023 - Taylor & Francis
Articular cartilage repair is a sophisticated process that has is being recently investigated.
There are several different approaches that are currently reported to promote cartilage …

Polynucleotides suppress inflammation and stimulate matrix synthesis in an in vitro Cell-based osteoarthritis model

SS Kuppa, HK Kim, JY Kang, SC Lee, HY Yang… - International Journal of …, 2023 - mdpi.com
Osteoarthritis (OA) is characterized by degeneration of the joint cartilage, inflammation, and
a change in the chondrocyte phenotype. Inflammation also promotes cell hypertrophy in …

Progress in the design and synthesis of viscosupplements for articular joint lubrication

G Gonzales, S Zauscher, S Varghese - Current Opinion in Colloid & …, 2023 - Elsevier
Throughout a lifetime, articular joints experience many loading cycles and are prone to
mechanical degradation. To safeguard the cartilage in these joints, the synovial fluid acts as …

Innovation in targeted intra-articular therapies for osteoarthritis

R Assi, J Quintiens, S Monteagudo, RJ Lories - Drugs, 2023 - Springer
Osteoarthritis is the most common chronic joint disease characterized by progressive
damage to the joints, leading to pain and loss of function. There is currently no cure or …