[HTML][HTML] Risk factors of severe COVID-19: a review of host, viral and environmental factors
The clinical course and outcome of COVID-19 are highly variable, ranging from
asymptomatic infections to severe disease and death. Understanding the risk factors of …
asymptomatic infections to severe disease and death. Understanding the risk factors of …
[HTML][HTML] Recent developments in frailty identification, management, risk factors and prevention: A narrative review of leading journals in geriatrics and gerontology
Frailty is an age-related clinical condition characterised by an increased susceptibility to
stressors and an elevated risk of adverse outcomes such as mortality. In the light of global …
stressors and an elevated risk of adverse outcomes such as mortality. In the light of global …
[HTML][HTML] Frailty impacts immune responses to Moderna COVID-19 mRNA vaccine in older adults
CT Semelka, ME DeWitt, MW Blevins, BC Holbrook… - Immunity & …, 2023 - Springer
Background Immune responses to COVID-19 mRNA vaccines have not been well
characterized in frail older adults. We postulated that frailty is associated with impaired …
characterized in frail older adults. We postulated that frailty is associated with impaired …
Two years with COVID-19: the Electronic Frailty Index identifies high-risk patients in the Stockholm GeroCovid Study
Introduction: Frailty, a measure of biological aging, has been linked to worse COVID-19
outcomes. However, as the mortality differs across the COVID-19 waves, it is less clear …
outcomes. However, as the mortality differs across the COVID-19 waves, it is less clear …
[HTML][HTML] Kinetics of the SARS-CoV-2 antibody avidity response following infection and vaccination
Serological assays capable of measuring antibody responses induced by previous infection
with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) have been critical …
with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) have been critical …
[HTML][HTML] T-cell mediated response after primary and booster SARS-CoV-2 messenger RNA vaccination in nursing home residents
I Schiavoni, A Palmieri, E Olivetta, P Leone… - Journal of the American …, 2023 - Elsevier
Objectives Nursing home (NH) residents have been significantly affected by the coronavirus
disease 2019 (COVID-19) pandemic. Studies addressing the immune responses induced by …
disease 2019 (COVID-19) pandemic. Studies addressing the immune responses induced by …
[HTML][HTML] Safety, effectiveness, and immunogenicity 6 months after BNT162B2 mRNA vaccine in frail nursing home residents
P Montejano-Hervás, J Gómez-Pavón… - Drugs & Aging, 2022 - Springer
Background Elderly people who reside in long-term care facilities form a frail and vulnerable
population, with multiple pathologies and high percentages of cognitive and functional …
population, with multiple pathologies and high percentages of cognitive and functional …
Vaccines for the prevention of coronavirus disease 2019 in older adults
OA Oyebanji, E Mylonakis… - Infectious Disease Clinics, 2023 - id.theclinics.com
Institutionalized and community-dwelling older adults have been greatly impacted by the
coronavirus disease 2019 (COVID-19) pandemic. 1 Older adults have a higher incidence of …
coronavirus disease 2019 (COVID-19) pandemic. 1 Older adults have a higher incidence of …
[HTML][HTML] Humoral immunogenicity assessment after receiving three types of SARS-CoV-2 vaccine
Several vaccines have been developed against SARS-CoV-2 and subsequently approved
by national/international regulators. Detecting specific antibodies after vaccination enables …
by national/international regulators. Detecting specific antibodies after vaccination enables …
[HTML][HTML] Humoral immune response after COVID-19 infection or BNT162b2 vaccine among older adults: evolution over time and protective thresholds
M Meyer, F Constancias, C Worth, A Meyer, M Muller… - Geroscience, 2022 - Springer
The objectives of this study were to assess the dynamics of the SARS-CoV-2 anti-RBD-IgG
response over time among older people after COVID-19 infection or vaccination and its …
response over time among older people after COVID-19 infection or vaccination and its …