Radiolabelling of nanomaterials for medical imaging and therapy
Nanomaterials offer unique physical, chemical and biological properties of interest for
medical imaging and therapy. Over the last two decades, there has been an increasing effort …
medical imaging and therapy. Over the last two decades, there has been an increasing effort …
A review of therapeutic challenges and achievements of methotrexate delivery systems for treatment of cancer and rheumatoid arthritis
Purpose Methotrexate (MTX) is one of the most widely studied and effective therapeutics
agents available to treat many solid tumors, hematologic malignancies, and autoimmune …
agents available to treat many solid tumors, hematologic malignancies, and autoimmune …
Current trends in the use of human serum albumin for drug delivery in cancer
Introduction Human serum albumin is the most abundant transport protein in plasma, which
has recently been extensively utilized to form nanoparticles for drug delivery in cancer. The …
has recently been extensively utilized to form nanoparticles for drug delivery in cancer. The …
Toxicity of multiwalled carbon nanotubes with end defects critically depends on their functionalization density
Carboxylated carbon nanotubes stand as the most promising nanovectors for biomedical
and pharmaceutical applications due to their ease of covalent conjugation with eclectic …
and pharmaceutical applications due to their ease of covalent conjugation with eclectic …
Hyaluronate tethered,“smart” multiwalled carbon nanotubes for tumor-targeted delivery of doxorubicin
The present study reports the optimized synthesis, physicochemical characterization, and
biological evaluation of a novel, multiwalled carbon nanotube-hyaluronic acid (MWCNT-HA) …
biological evaluation of a novel, multiwalled carbon nanotube-hyaluronic acid (MWCNT-HA) …
Gelatin coated hybrid lipid nanoparticles for oral delivery of amphotericin B
S Jain, PU Valvi, NK Swarnakar… - Molecular …, 2012 - ACS Publications
Amphotericin B (AmB) loaded polymer lipid hybrid nanoparticles (AmB-PLNs) comprised of
lecithin (anionic lipid) and gelatin (Type A, cationic below its isoelectric point 7.0–9.0) were …
lecithin (anionic lipid) and gelatin (Type A, cationic below its isoelectric point 7.0–9.0) were …
Augmented anticancer activity of a targeted, intracellularly activatable, theranostic nanomedicine based on fluorescent and radiolabeled, methotrexate-folic acid …
The present study reports the design, synthesis, and biological evaluation of a novel,
intravenously injectable, theranostic prodrug based on multiwalled carbon nanotubes …
intravenously injectable, theranostic prodrug based on multiwalled carbon nanotubes …
Paclitaxel loaded PEGylated gleceryl monooleate based nanoparticulate carriers in chemotherapy
A PEGylated drug delivery system of paclitaxel (PTX), based on glyceryl monooleate (GMO)
was prepared by optimizing various parameters to explore its potential in anticancer therapy …
was prepared by optimizing various parameters to explore its potential in anticancer therapy …
Fucose decorated solid-lipid nanocarriers mediate efficient delivery of methotrexate in breast cancer therapeutics
The present study is designed to engineer fucose anchored methotrexate loaded solid lipid
nanoparticles (SLNs) to target breast cancer. The developed nano-carriers were …
nanoparticles (SLNs) to target breast cancer. The developed nano-carriers were …
Improved cisplatin delivery in cervical cancer cells by utilizing folate-grafted non-aggregated gelatin nanoparticles
Purpose Cisplatin is highly effective in the treatment of cervical cancer. However, in
therapeutic doses, cisplatin induces several adverse effects due to undesirable tissue …
therapeutic doses, cisplatin induces several adverse effects due to undesirable tissue …