The innate immune system comprises a cellular and a humoral arm. Humoral pattern
recognition molecules include complement components, collectins, ficolins, and pentraxins …

The pentraxin is a superfamily of proteins with the same domain known as the pentraxin
domain at C-terminal. This family has two subgroups, namely; short pentraxins (C-reactive …

Abstract Pentraxin-3 (PTX3) belongs to the pentraxine family, innate immune regulators
involved in angiogenesis, proliferation and immune escape in cancer. Here, we evaluated …

Cutaneous melanoma is one of the most aggressive cancers characterized by a high
plasticity, a propensity for metastasis, and drug resistance. Melanomas are composed of …

Abstract Introduction Pentraxin 3 (PTX3) is an essential regulator of the immune system.
However, the immune‐modulatory role of PTX3 in the tumor microenvironment of glioma has …

Abstract Pentraxin-3 (PTX3) is the prototype of the long pentraxin subfamily, an acute-phase
protein consisting of a C-terminal pentraxin domain and a unique N-terminal domain. PTX3 …

Since its discovery in 1992, long pentraxin 3 (PTX3) has been characterized as soluble
patter recognition receptor, a key player of the innate immunity arm with non-redundant …

Epithelial-mesenchymal transition (EMT) as a trans-differentiation program and a key
process in tumor progression is linked positively with increased expansion of cancer stem …

The use of three-dimensional (3D) bioprinting has been proposed for the reproducible
production of 3D disease models that can be used for high-throughput drug testing and …

Mutations in the Krebs cycle enzyme IDH1 (isocitrate dehydrogenase (NADP (+)) 1) are
associated with better prognosis in gliomas. Though IDH1 mutant (IDH1R132H) tumors are …