Topography of the extracellular environment is now recognized as a major biophysical
regulator of cell behavior and function. The study of the influence of patterned substrates on …

Cells sense and respond to a variety of physical cues from their surrounding
microenvironment, and these are interpreted through mechanotransductive processes to …

The intrinsic architecture of biological tissues and of implanted biomaterials provides cells
with large-scale geometrical cues. To understand how cells are able to sense and respond …

The demand for artificial organs has greatly increased because of various aging-associated
diseases and the wide need for organ transplants. A recent trend in tissue engineering is the …

Chronic tympanic membrane (TM) perforations can cause otorrhea. To date, various types of
tissue engineering techniques have been applied for the regeneration of chronic TM …

Nanoscale biomaterials have garnered immense interest in the scientific community in the
recent decade. This review specifically focuses on the application of three nanomaterials, ie …

Peripheral nerve injuries persist as a major clinical issue facing the US population and can
be caused by stretch, laceration, or crush injuries. Small nerve gaps are simple to treat, and …

Future-oriented material fabrication technologies would aim to reproduce features
characteristic to the natural materials into the synthetic ones. Various bio-mimicking …

Stem cells derived from dental tissues—dental stem cells—are favored due to their easy
acquisition. Among them, dental pulp stem cells (DPSCs) extracted from the dental pulp …

This paper describes the fabrication of a structural scaffold consisting of both randomly
oriented nanofibers and triangular prism patterns on the scaffold surface using a …