Although fire is now rarely used in synthetic chemistry, it was not until Robert Bunsen
invented the burner in 1855 that the energy from this heat source could be applied to a …

A CO group richer:(Hetero) arenes are vital intermediates in the manufacture of
agrochemicals, dyes, pharmaceuticals, and other industrial products. In the past decades …

Within the past decade, green chemistry has attained the status of a major scientific
discipline. 1, 2 The investigation and application of green chemistry principles has led to the …

The past half century has witnessed enormous growth in transition-metal organometallic
chemistry, both as a scientific discipline and as a subject for research and applications in …

Transition metal catalyzed carbonylation reactions using carbon monoxide as the C-1
source have occupied an all important position in catalysis which is subsequently related to …

The palladium-catalyzed carbonylation of aryl and vinyl halides was first described more
than 30 years ago by Richard Heck. However, limitations in the conditions originally …

Progress in organometallic catalysis began with the discovery of the Roelen reaction
(hydroformylation with carbon monoxide and hydrogen) in 1938 and the Reppe reaction …

The use of microwave irradiation in organic synthesis has become increasingly popular
within the pharmaceutical and academic arenas, because it is a new enabling technology …

Peptide modifications can unlock a variety of compounds with structural diversity and
abundant biological activity. In nature, peptide modifications, such as functionalisation at the …

Microwave technology has become very important in synthesis and it is reasonable to assert
that there are now very few areas of synthetic organic chemistry that have not been shown to …