The role of the extracellular matrix (ECM) in wound healing: a review

RB Diller, AJ Tabor - Biomimetics, 2022 - mdpi.com
The extracellular matrix (ECM) is a 3-dimensional structure and an essential component in
all human tissues. It is comprised of varying proteins, including collagens, elastin, and …

Metal–organic frameworks and their composites for chronic wound healing: from bench to bedside

Y Xiong, Q Feng, L Lu, X Qiu, S Knoedler… - Advanced …, 2024 - Wiley Online Library
Chronic wounds are characterized by delayed and dysregulated healing processes. As
such, they have emerged as an increasingly significant threat. The associated morbidity and …

An immunomodulatory hydrogel by hyperthermia‐assisted self‐cascade glucose depletion and ROS scavenging for diabetic foot ulcer wound therapeutics

X Qi, E Cai, Y Xiang, C Zhang, XX Ge… - Advanced …, 2023 - Wiley Online Library
Current therapeutic protocols for diabetic foot ulcers (DFUs), a severe and rapidly growing
chronic complication in diabetic patients, remain nonspecific. Hyperglycemia‐caused …

Scarless wound healing programmed by core-shell microneedles

Y Zhang, S Wang, Y Yang, S Zhao, J You… - Nature …, 2023 - nature.com
Effective reprogramming of chronic wound healing remains challenging due to the limited
drug delivery efficacy hindered by physiological barriers, as well as the inappropriate dosing …

Biomaterials releasing drug responsively to promote wound healing via regulation of pathological microenvironment

H Li, B Li, D Lv, W Li, Y Lu, G Luo - Advanced Drug Delivery Reviews, 2023 - Elsevier
Wound healing is characterized by complex, orchestrated, spatiotemporal dynamic
processes. Recent findings demonstrated suitable local microenvironments were …

Degradable biomedical elastomers: paving the future of tissue repair and regenerative medicine

B Jia, H Huang, Z Dong, X Ren, Y Lu… - Chemical Society …, 2024 - pubs.rsc.org
Degradable biomedical elastomers (DBE), characterized by controlled biodegradability,
excellent biocompatibility, tailored elasticity, and favorable network design and …

Mechano‐activated cell therapy for accelerated diabetic wound healing

Y Shou, Z Le, HS Cheng, Q Liu, YZ Ng… - Advanced …, 2023 - Wiley Online Library
Chronic diabetic wounds are a significant global healthcare challenge. Current strategies,
such as biomaterials, cell therapies, and medical devices, however, only target a few …

Fabrication and characterization of PVA@ PLA electrospinning nanofibers embedded with Bletilla striata polysaccharide and Rosmarinic acid to promote wound …

G Zhong, M Qiu, J Zhang, F Jiang, X Yue… - International Journal of …, 2023 - Elsevier
In this study, a novel nanofiber material with Polylactic acid (PLA), natural plant
polysaccharides-Bletilla striata polysaccharide (BSP) and Rosmarinic acid (RA) as the raw …

Cellulose‐Based pH‐Responsive Janus Dressing with Unidirectional Moisture Drainage for Exudate Management and Diabetic Wounds Healing

Z Xu, J Fan, W Tian, X Ji, Y Cui, Q Nan… - Advanced Functional …, 2024 - Wiley Online Library
Diabetic wounds with hyperglycemic tissue exudates and bacterial infections have become
a great challenge that seriously delays the healing of diabetic wounds. Therefore …

On‐Demand Removable Self‐Healing and pH‐Responsive Europium‐Releasing Adhesive Dressing Enables Inflammatory Microenvironment Modulation and …

M Fu, Y Zhao, Y Wang, Y Li, M Wu, Q Liu, Z Hou, Z Lu… - Small, 2023 - Wiley Online Library
Current diabetic wound treatments remain unsatisfactory due to the lack of a comprehensive
strategy that can integrate strong applicability (tissue adhesiveness, shape adaptability, fast …