Safety, tolerability, and risks associated with first-and second-generation antipsychotics: a state-of-the-art clinical review
M Solmi, A Murru, I Pacchiarotti… - … and clinical risk …, 2017 - Taylor & Francis
Since the discovery of chlorpromazine (CPZ) in 1952, first-generation antipsychotics (FGAs)
have revolutionized psychiatric care in terms of facilitating discharge from hospital and …
have revolutionized psychiatric care in terms of facilitating discharge from hospital and …
Life expectancy and years of potential life lost in bipolar disorder: systematic review and meta-analysis
Background There is increasing research examining excess mortality in people with bipolar
disorder using life expectancy and related measures, which quantify the disease impact on …
disorder using life expectancy and related measures, which quantify the disease impact on …
Genome-wide association study of more than 40,000 bipolar disorder cases provides new insights into the underlying biology
Bipolar disorder is a heritable mental illness with complex etiology. We performed a genome-
wide association study of 41,917 bipolar disorder cases and 371,549 controls of European …
wide association study of 41,917 bipolar disorder cases and 371,549 controls of European …
Comorbidities and mortality in bipolar disorder: a Swedish national cohort study
C Crump, K Sundquist, MA Winkleby… - JAMA psychiatry, 2013 - jamanetwork.com
Importance Bipolar disorder is associated with premature mortality, but the specific causes
and underlying pathways are unclear. Objective To examine the physical health effects of …
and underlying pathways are unclear. Objective To examine the physical health effects of …
Patterns of tobacco-related mortality among individuals diagnosed with schizophrenia, bipolar disorder, or depression
RC Callaghan, S Veldhuizen, T Jeysingh… - Journal of psychiatric …, 2014 - Elsevier
Even though individuals with psychiatric conditions have a prevalence of smoking
approximately 2–4 times greater than the general population, surprisingly little evidence …
approximately 2–4 times greater than the general population, surprisingly little evidence …
Shared metabolic and immune-inflammatory, oxidative and nitrosative stress pathways in the metabolic syndrome and mood disorders
LGP de Melo, SOV Nunes, G Anderson… - Progress in Neuro …, 2017 - Elsevier
This review examines the shared immune-inflammatory, oxidative and nitrosative stress
(IO&NS) and metabolic pathways underpinning metabolic syndrome (MetS), bipolar disorder …
(IO&NS) and metabolic pathways underpinning metabolic syndrome (MetS), bipolar disorder …
Inflammation as a neurobiological substrate of cognitive impairment in bipolar disorder: evidence, pathophysiology and treatment implications
JD Rosenblat, E Brietzke, RB Mansur… - Journal of affective …, 2015 - Elsevier
Background Bipolar disorder (BD) has been associated with cognitive impairment during
depressed, manic and euthymic periods. Inflammation has been shown to be involved in the …
depressed, manic and euthymic periods. Inflammation has been shown to be involved in the …
Call to action regarding the vascular‐bipolar link: a report from the Vascular Task Force of the International Society for Bipolar Disorders
Objectives The association of bipolar disorder with early and excessive cardiovascular
disease was identified over a century ago. Nonetheless, the vascular‐bipolar link remains …
disease was identified over a century ago. Nonetheless, the vascular‐bipolar link remains …
Smoking and the risk for bipolar disorder: evidence from a bidirectional Mendelian randomisation study
BackgroundThere is increasing evidence that smoking is a risk factor for severe mental
illness, including bipolar disorder. Conversely, patients with bipolar disorder might smoke …
illness, including bipolar disorder. Conversely, patients with bipolar disorder might smoke …
Assessment and treatment of mood disorders in the context of substance abuse
BK Tolliver, RF Anton - Dialogues in clinical neuroscience, 2015 - Taylor & Francis
Recognition and management of mood symptoms in individuals using alcohol and/or other
drugs represent a daily challenge for clinicians in both inpatient and outpatient treatment …
drugs represent a daily challenge for clinicians in both inpatient and outpatient treatment …