Type IV pilin proteins: versatile molecular modules

CL Giltner, Y Nguyen, LL Burrows - Microbiology and molecular …, 2012 - Am Soc Microbiol
SUMMARY Type IV pili (T4P) are multifunctional protein fibers produced on the surfaces of a
wide variety of bacteria and archaea. The major subunit of T4P is the type IV pilin, and …

Colonization factors of enterotoxigenic Escherichia coli

TPV Madhavan, H Sakellaris - Advances in applied microbiology, 2015 - Elsevier
Enterotoxigenic Escherichia coli (ETEC) is a major cause of life-threatening diarrheal
disease around the world. The major aspects of ETEC virulence are colonization of the small …

Cryoelectron microscopy reconstructions of the Pseudomonas aeruginosa and Neisseria gonorrhoeae type IV pili at sub-nanometer resolution

F Wang, M Coureuil, T Osinski, A Orlova, T Altindal… - Structure, 2017 - cell.com
We report here cryoelectron microscopy reconstructions of type IV pili (T4P) from two
important human pathogens, Pseudomonas aeruginosa and Neisseria gonorrhoeae, at∼ 8 …

Motility and adhesion through type IV pili in Gram-positive bacteria

KH Piepenbrink, EJ Sundberg - Biochemical Society …, 2016 - portlandpress.com
Type IV pili are hair-like bacterial surface appendages that play a role in diverse processes
such as cellular adhesion, colonization, twitching motility, biofilm formation, and horizontal …

Landmark discoveries and recent advances in type IV pilus research

PK Singh, J Little, MS Donnenberg - Microbiology and Molecular …, 2022 - Am Soc Microbiol
SUMMARY Type IV pili (T4P) are retractable multifunctional nanofibers present on the
surface of numerous bacterial and archaeal species. Their importance to microbiology is …

Cryo-electron microscopy reveals two distinct type IV pili assembled by the same bacterium

A Neuhaus, M Selvaraj, R Salzer, JD Langer… - Nature …, 2020 - nature.com
Type IV pili are flexible filaments on the surface of bacteria, consisting of a helical assembly
of pilin proteins. They are involved in bacterial motility (twitching), surface adhesion, biofilm …

Structural and evolutionary analyses show unique stabilization strategies in the type IV pili of Clostridium difficile

KH Piepenbrink, GA Maldarelli, CFM De La Peña… - Structure, 2015 - cell.com
Type IV pili are produced by many pathogenic Gram-negative bacteria and are important for
processes as diverse as twitching motility, biofilm formation, cellular adhesion, and …

Genetic control of asexual development in Aspergillus fumigatus

F Alkhayyat, SC Kim, JH Yu - Advances in applied microbiology, 2015 - Elsevier
Aspergillus fumigatus is one of the most common fungi found in the environment. It is an
opportunistic human pathogen causing invasive pulmonary aspergillosis with a high …

Structural basis for the toxin-coregulated pilus–dependent secretion of Vibrio cholerae colonization factor

H Oki, K Kawahara, M Iimori, Y Imoto, H Nishiumi… - Science …, 2022 - science.org
Colonization of the host intestine is the most important step in Vibrio cholerae infection. The
toxin-coregulated pilus (TCP), an operon-encoded type IVb pilus (T4bP), plays a crucial role …

The Vibrio cholerae minor pilin TcpB mediates uptake of the cholera toxin phage CTXϕ

M Gutierrez-Rodarte, S Kolappan, BA Burrell… - Journal of Biological …, 2019 - ASBMB
Virulent strains of the bacterial pathogen Vibrio cholerae cause the diarrheal disease
cholera by releasing cholera toxin into the small intestine. V. cholerae acquired its cholera …