Metal-based nanowires in electrical biosensing

SJ Zhong, KY Chen, SL Wang, F Manshaii, N Jing… - Rare Metals, 2024 - Springer
Harnessing the unique attributes of metal-based nanowires (MNWs), such as their
adaptability, high aspect ratio and conductivity, this review elucidates their burgeoning role …

Advancements in CRISPR-Diagnostic Techniques for Rapid on-site Monitoring of Environmental Virus

Z Deng, W Liao, L Bu, J Li, J Li, L Wang, A Yuan… - TrAC Trends in …, 2024 - Elsevier
Highly sensitive and rapid environmental surveillance is crucial due to the significant role of
various environmental media in transmitting multiple viruses. Specifically, when examining …

Ultrasensitive DNA Origami Plasmon Sensor for Accurate Detection in Circulating Tumor DNAs

Z Chen, C Meng, X Wang, J Chen… - Laser & Photonics …, 2024 - Wiley Online Library
Early lung cancer screening by computed tomography is hampered by pulmonary nodules
caused by massive COVID‐19 infections, necessitating an ultrasensitive approach for the …

SEDphone: Spatial encoding of centrifugal microfluidic disc integrated smartphone-controlled platform via RT/LAMP-CRISPR/Cas12a system for influenza virus …

X Yin, Z Wang, H You, T Shu, C Hua, J Zhao… - Sensors and Actuators B …, 2024 - Elsevier
Accurate and rapid identification of multiple pathogens simultaneously is paramount for
global public health, including the detection of different influenza virus subtypes. Recently …

CRISPR-powered microfluidic biosensor for preamplification-free detection of ochratoxin A

C Wu, Y Yue, B Huang, H Ji, L Wu, H Huang - Talanta, 2024 - Elsevier
The CRISPR technology, which does not require complex instruments, expensive reagents
or professional operators, has attracted a lot of attention. When utilizing the CRISPR-Cas …

RT-RPA-assisted CRISPR/Cas12a for rapid and multiplex detection of respiratory infectious viruses based on centrifugal microfluidics

R Peng, Z Lu, M Liu, F Hu - Sensors and Actuators B: Chemical, 2024 - Elsevier
Clustered regularly interspaced short palindromic repeats (CRISPR)-based nucleic acid
detection technology combined with recombinase polymerase amplification (RPA) allows for …

Amplification-free orthogonal CRISPR/Cas system for rapid discrimination of bacterial vs viral infection in febrile children

F Liu, T An, C Zhou, W Chen, R Huang… - Sensors and Actuators B …, 2024 - Elsevier
Bacterial and viral infections are one of the most common reasons for febrile children to seek
medical attention. Among these cases, only 5–10% of cases are bacterial infection that …

An ultra-sensitive suboptimal protospacer adjacent motif enhanced rolling circle amplification assay based on CRISPR/Cas12a for detection of miR-183

Z Lu, S Wang, P Li, H Yang, S Han… - … in Bioengineering and …, 2024 - frontiersin.org
Introduction MicroRNAs (miRNAs) have been recognized as promising diagnostic
biomarkers for Diabetic Retinopathy (DR) due to their notable upregulation in individuals …

A low-temperature digital microfluidic system used for protein–protein interaction detection

J Shen, J Liao, H Liu, C Liu, C Li, H Cheng, H Yang… - Lab on a Chip, 2023 - pubs.rsc.org
The occurrence, development and prediction of various biological processes and diseases
are inseparable from the protein–protein interaction (PPI), so it is extremely meaningful to …

Ratiometric nonfluorescent CRISPR assay utilizing Cas12a-induced plasmid supercoil relaxation

N Mohammad, L Talton, S Dalgan, Z Hetzler… - Communications …, 2024 - nature.com
Most CRISPR-based biosensors rely on labeled reporter molecules and expensive
equipment for signal readout. A recent approach quantifies analyte concentration by sizing λ …